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- What is amlodipine and valsartan, and how does it work (mechanism of action)?
- What brand names are available for amlodipine and valsartan?
- Is amlodipine and valsartan available as a generic drug?
- Do I need a prescription for amlodipine and valsartan?
- What are the side effects of amlodipine and valsartan?
- What is the dosage for amlodipine and valsartan?
- Which drugs or supplements interact with amlodipine and valsartan?
- Is amlodipine and valsartan safe to take if I'm pregnant or breastfeeding?
- What else should I know about amlodipine and valsartan?
What is amlodipine and valsartan, and how does it work (mechanism of action)?
Amlodipine belongs to a class of drugs called calcium channel blockers. These medications block the transport of calcium into the smooth muscle cells lining the coronary arteries and other arteries of the body. Since calcium is important in promoting contraction of muscles, blocking calcium transport relaxes the muscles that surround arteries, dilating (enlarging) the arteries of the body including the arteries of the heart (coronary arteries). Dilating arteries lowers blood pressure.
Valsartan is an oral drug that belongs to a class of drugs called angiotensin receptor blockers (ARBs) . Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE) on a chemical in blood called angiotensinogen. Angiotensin is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells surrounding blood vessels. Angiotensin's attachment to the receptors causes the blood vessels to narrow (constrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure.
What brand names are available for amlodipine and valsartan?
Is amlodipine and valsartan available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for amlodipine and valsartan?
What are the side effects of amlodipine and valsartan?
Side effects include:
- abdominal pain,
- diarrhea and
- reduced renal function, and
- allergic reactions.
Angioedema (swelling of soft tissues including those of the throat and larynx) is a rare but serious side effect of valsartan.
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