SIDE EFFECTS: Lotrel causes the same side effects as benazepril and amlodipine. Common side of Lotrel include:
- water retention (edema) in legs and arms,
- stomach pain,
- muscle cramps,
- sexual problems, and
GENERIC AVAILABLE: Yes
PREPARATIONS: Capsules (mg amlodipine/mg benazepril): 2.5/10; 5/10;5/20; 5/40; 10/20; and 10/40
STORAGE: Lotrel should be stored at room temperature, 15 C - 30 C (59 C - 86 F).
DOSING: The dose of Lotrel is tailored to the patient's needs. The dose is one capsule once daily.
DRUG INTERACTIONS: Combining benazepril with potassium supplements, potassium containing salt substitutes, and potassium conserving diuretics such as amiloride (Moduretic), spironolactone (Aldactone), and triamterene (Dyazide, Maxzide), can lead to dangerously high blood levels of potassium.
There have been reports of increased lithium (Eskalith, Lithobid) levels when lithium is used in combination with ACE inhibitors. The reason for this interaction is not known, but the increased levels may lead to toxicity from lithium.
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