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February 8, 2012

amlodipine and benazepril, Lotrel

GENERIC NAME: amlodipine and benazepril

BRAND NAME: Lotrel

DRUG CLASS AND MECHANISM: Lotrel is a combination product, containing benazepril (Lotensin) and amlodipine (Norvasc). For more information on these two drugs, please see the individual generic drug articles in the "Medications" section.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Capsules: 2.5mg amlodipine/10mg benazepril; 5mg amlodipine/20mg benazepril; 5mg amlodipine/40mg benazepril; 10mg amlodipine/20mg benazepril; 10mg amlodipine/40mg benazepril;

STORAGE: Norvasc should be stored below 86 F (30 C) in a tight, light resistant container.

PRESCRIBED FOR: Lotrel is used for treating high blood pressure.

DOSING: The dose of Lotrel is tailored to the patient's needs.

DRUG INTERACTIONS: This is a combination drug. Please refer to both the benazepril (Lotensin) and amlodipine (Norvasc) articles.

PREGNANCY: This is a combination drug. Please refer to both benazepril (Lotensin) and amlodipine (Norvasc) articles.

NURSING MOTHERS: This is a combination drug. Please refer to both benazepril (Lotensin) and amlodipine (Norvasc) articles.

SIDE EFFECTS: This is a combination drug. Please refer to both benazepril (Lotensin) and amlodipine (Norvasc) articles.

Reference: FDA Prescribing Information


Last Editorial Review: 7/12/2010




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      • High blood pressure, also known as hypertension, is a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90. There are two causes of high blood pressure, primary and secondary. Primary high blood pressure is much more common that secondary and its basic causes or underlying defects are not always known. It is known that a diet high in salt increases the risk for high blood pressure, as well as high cholesterol. Genetic factors are also a primary cause. Secondary high blood pressure is generally caused by another condition such as renal hypertension, tumors, and other conditions. Treatment for high blood pressure is generally lifestyle changes and if necessary, diet.
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      • High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
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Related Drugs - WebMD Health Network

amlodipine and benazepril, Lotrel

What is high blood pressure?

High blood pressure (HBP) or hypertension means high pressure (tension) in the arteries. Arteries are vessels that carry blood from the pumping heart to all the tissues and organs of the body. High blood pressure does not mean excessive emotional tension, although emotional tension and stress can temporarily increase blood pressure. Normal blood pressure is below 120/80; blood pressure between 120/80 and 139/89 is called "pre-hypertension", and a blood pressure of 140/90 or above is considered high.

The top number, the systolic blood pressure, corresponds to the pressure in the arteries as the heart contracts and pumps blood forward into the arteries. The bottom number, the diastolic pressure, represents the pressure in the arteries as the heart relaxes after the contraction. The diastolic pressure reflects the lowest pressure to which the arteries are exposed.

An elevation of the systolic and/or diastolic blood pressure increas...

Read the High Blood Pressure article »







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