perphenazine and amitriptyline hydrochloride (Etrafon - brand no longer available in the US) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of antidepressants in a child or adolescent must balance this risk of suicide with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts, or unusual changes in behavior.

Elderly patients with dementia related psychosis treated with antipsychotics are at an increased risk of death.

REFERENCES:

FDA Prescribing Information.

Medscape. amitriptyline/perphenazine.


Medically Reviewed by a Doctor on 8/11/2014


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