GENERIC NAME: AMITRIPTYLINE W/PERPHENAZINE - ORAL (am-eh-TRIP-teh-leen WITH per-FEN-uh-zeen)
BRAND NAME(S): Etrafon, Triavil
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This combination medication is used to treat depression, anxiety and agitation. The amitriptyline component is an antidepressant which elevates depressed moods. Perphenazine relieves anxiety and agitation.
HOW TO USE: Take this as prescribed. Try to take each dose at the same time(s) each day so you remember to routinely take it. Keep all appointments with your doctor. Your dose of this medication may be changed a few times at first to find the best dose for you.
SIDE EFFECTS: May cause drowsiness, dizziness, increased sun sensitivity or blurred vision. May initially cause dizziness and lightheadedness when rising too quickly from a sitting or lying position. Other side effects include heartburn, increased appetite, dry mouth, strange taste in mouth, anxiety, restlessness or sweating. If these effects persist or worsen, notify your doctor promptly. Notify your doctor promptly if you develop: chest pain, a rapid or irregular heartbeat, difficulty urinating, nightmares, excessive drowsiness, tremor, uncontrollable movements of the mouth/tongue/face, muscle stiffness or weakness in the arms or legs, fainting, uncoordinated movements, ringing in the ears, confusion. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug tell your doctor your medical history, especially of: glaucoma, prostate problems, decreased urine output, thyroid disease, breathing problems, seizure problems, alcohol use, heart disease, mental/emotional problems, liver or kidney disease, drug allergies. This medication can increase sensitivity to sunlight. Avoid prolonged sun exposure. Wear a sunscreen and protective clothing. Limit alcohol while using this drug to avoid excessive drowsiness. Caution is advised when performing tasks requiring alertness (e.g., driving). Though uncommon, depression itself can lead to thoughts or attempts of suicide. Tell your doctor immediately if you have any suicidal thoughts or other mental/mood changes. Keep all medical appointments so your doctor can monitor your progress closely. Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects of the drug. This drug should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and may have an effect on a nursing infant. Consult your doctor before breast-feeding.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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