amiodarone, Cordarone, Nextrone, Pacerone (cont.)

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Medical and Pharmacy Editor:

Amiodarone was discovered in 1961 and approved by the FDA in December 1985.

PRESCRIBED FOR: Amiodarone is approved for recurrent ventricular fibrillation and hemodynamically unstable ventricular tachycardia.

SIDE EFFECTS: Amiodarone has many side effects and several that are serious. This is only a partial list. Common side effects include:

Amiodarone is also associated with:



PREPARATIONS: Tablets: 100, 200 mg. Injection: 50 mg/ml., 1.5 g/ml., 1.8 g/ml.

STORAGE: Tablets and injection should be kept at room temperature, 20 C to 25 C (68 F to 77 F).

DOSING: The recommended dosing schedule is an initial loading dose of 800-1600 mg daily for 1 to 3 weeks, followed by 600-800 mg daily for 1 month, then 400 mg daily for maintenance. Response should be closely monitored and dosing is individualized for each patient. Amiodarone may be administered once daily or given twice daily with meals to minimize stomach upset which is seen more frequently with higher doses.

Medically Reviewed by a Doctor on 1/21/2015

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