AMIODARONE-INJECTION, Cordarone

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DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: agalsidase beta, dofetilide, certain HIV protease inhibitors (nelfinavir, ritonavir), quinupristin/dalfopristin. If you are currently using any of these medications, tell your doctor or pharmacist before starting amiodarone. Other drugs besides amiodarone which may affect the heart rhythm (QTc prolongation in the EKG) include flecainide, disopyramide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: local and general anesthesia, "blood thinners" (e.g., warfarin), cimetidine, cyclosporine, digoxin, fentanyl, heart medications (e.g., diltiazem, verapamil, beta-blockers such as propranolol), other HIV protease inhibitors (e.g., amprenavir, indinavir), methotrexate, phenytoin, rifampin, "statins" (e.g., lovastatin, simvastatin), St. John's wort. Do not start or stop any medicine without doctor or pharmacist approval.

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Heart Disease Pictures Slideshow: Coronary Artery Disease
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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