GENERIC NAME: Amikacin sulfate
DISCONTINUED BRAND: Amikin
DRUG CLASS AND MECHANISM: Amikacin is a man-made aminoglycoside antibiotic. It is similar to tobramycin and gentamicin. Amikacin binds to components of bacteria that produce important bacterial proteins, blocking protein synthesis which eventually leads to stopping further bacterial growth. Amikacin is used to treat infections caused by bacteria that are resistant to gentamicin and tobramycin. Amikacin treats infections caused by gram-negative bacteria such as Pseudomonas species, Escherichia coli, Providencia species, Indole-positive and indole-negative Proteus species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter. Amikacin is also used in certain staphylococcal infections as well.
PRESCRIBED FOR: Amikacin is used for serious bacterial infections like bacterial meningitis, infected burns, cystic fibrosis, and severe urinary tract infections. It used when the infecting organism is resistant to tobramycin and gentamicin.
SIDE EFFECTS: Side effects of Amikacin are:
- hearing loss,
- kidney dysfunction,
- loss of balance,
- muscular paralysis,
- headache, and
- low blood pressure.
Amikacin carries a boxed warning of loss of hearing and kidney dysfunction for individuals treated with high doses or for longer periods.
GENERIC AVAILABLE: Yes
PREPARATIONS: Amikacin sulfate injection is colorless solution. It is available in 50 mg/ml and 250 mg/ml strengths in 2 ml vials. It is also available in 250 mg/ml strength in 4 ml vials.
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