GENERIC NAME: AMIFOSTINE - INJECTION (am-ih-FOSS-teen)
BRAND NAME(S): Ethyol
Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
USES: This medication is used to reduce the risk of kidney problems caused by the use of cisplatin or to reduce dry mouth caused by radiation treatment.
OTHER USES: This drug may also be used for prevention of lung damage caused by the use of paclitaxel.
HOW TO USE: This medication is injected into a vein before cancer treatment. Use exactly as directed by the doctor. This drug is given while the person is lying down to minimize dizziness. Medication to prevent nausea and vomiting may be given along with this drug.
SIDE EFFECTS: Flushed/warm or chills/cool sensations, dizziness, drowsiness, hiccups, sneezing, nausea/vomiting might occur. If these persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of the following highly unlikely but very serious side effects occur: fainting episodes, irregular heartbeat, seizures, muscle twitching/cramping. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: fever, rash, itching, severe dizziness, swelling, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), blood vessel or heart disease, very low or high blood pressure, kidney disease. If you are taking medication to treat high blood pressure, your doctor may recommend a change in your dose a day before your amifostine infusion to minimize side effects. Consult your doctor for details. Limit alcohol use as this may increase the drowsiness effect of this medication. Caution performing tasks requiring mental alertness if this medicine causes drowsiness or dizziness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether is excreted into breast milk. Consult your doctor before breast-feeding. Caution is advised when this drug is used in the elderly.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Dry Mouth - Read about dry mouth causes (dehydration, diabetes, Sjogren's syndrome, medications for allergies and anxiety), symptoms (sore throat, raw tongue) and treatment.
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