amantadine (Symmetrel - Discontinued) (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
SIDE EFFECTS: The most frequent side effects associated with amantadine that can appear after a few hours or several days of therapy include:
Less common side effects include:
GENERIC AVAILABLE: No
PREPARATIONS: Capsule: 100 mg. Syrup: 50 mg/5 ml (teaspoon).
STORAGE: Amantadine should be stored at room temperature between 15-30 C (59- 86 F).
DOSING: Amantadine is taken once or twice daily with or without food. If it causes an upset stomach, it can be taken with food. The dosage for prevention and treatment of influenza A infections in adults is 200 mg daily. For treatment of influenza, amantadine should be started within 24 to 48 hours after the onset of signs or symptoms and should be continued for 24 to 48 hours after the disappearance of signs or symptoms. To prevent influenza, amantadine should be started as soon as possible after exposure to the influenza virus and continued for at least 10 days. Persons with reduced kidney function and elderly persons may need lower doses (or less frequent doses).
The dosage for treating Parkinson's or extrapyramidal symptoms is 100 mg twice daily.
DRUG INTERACTIONS: Amantadine adds to the sedating effects of alcohol and other sedating drugs such as:
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