altretamine, Hexalen

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Cervical Cancer Slideshow Pictures

GENERIC NAME: altretamine

BRAND NAME: Hexalen

DRUG CLASS AND MECHANISM: Altretamine is an oral drug that is used to treat ovarian cancer. The precise mechanism by which altretamine exerts its anti-cancer effect is unknown. It was approved by the FDA in 1990.

PRESCRIBED FOR: Altretamine is used for the treatment of ovarian cancer that has persisted or has recurred following treatment with other anti-cancer drugs. Although not an approved use, altretamine also has been used for treating lung cancer.

SIDE EFFECTS: Common side effects are:

PRESCRIPTION: Yes.

GENERIC AVAILABLE: No.

PREPARATIONS: Capsules of 50 mg.

STORAGE: Capsules should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

White blood cell counts and platelet counts may drop with altretamine treatment, increasing the risk of infection and bleeding, respectively.

DOSING: The dose of altretamine is 260 mg/square meter/day. Altretamine may be taken either for 14 or 21 consecutive days as part of one or more 28 day cycles. The total daily dose generally is split into four oral doses, one oral dose after each meal and at bedtime.

Medically Reviewed by a Doctor on 6/11/2015
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: altretamine on RxList
RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Cancer Report Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors