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My My GP prescribed Effexor in January. Hot flashes were frequent each day (and also at night), plus I felt anxious, was crabby (not usual for me) with no tolerance for stupidity! I also had difficulty sleeping, so lack of sleep wasn't helping my general frame of mind. I didn't feel like "myself" and I often wondered where an outburst had come from! After about 3 weeks, the hot flashes disappeared and I was ecstatic. After another 3-4 weeks I felt back to normal again no mood swings, I didn't feel anxious etc. and sleep was back to normal. After about 3 months, though, I started to get a bit anxious again, so I went to max dose of XR. It's now July and I feel great except the hot flashes are as regular as they were before I started, and have been for around the last 5 months. I have tried Black Cohosh, "Harmony" tablets no noticeable difference. I am now resigned to having to put up with them, and always carry an elegant fan, so I can help my face cool down. With each hot flash, the sweat (it's not perspiration or a "glow") runs down my face and neck, and down my back. It's horrible, but what can I do? Thank goodness for Effexor, though. Published: August 17 ::