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February 10, 2012
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alteplase for iv catheters - injection, Cathflo Activase

GENERIC NAME: ALTEPLASE FOR IV CATHETERS - INJECTION (AL-te-plase)

BRAND NAME(S): Cathflo Activase

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to dissolve blood clots that may form within certain tubes (catheters) used for intravenous (IV) injections. IV catheters are used in people who need to regularly receive injections into a vein during treatment (e.g., chemotherapy, dialysis). Blood clots that block the catheter prevent its use and can make it necessary to replace the catheter. This medication can prevent the need to place a new catheter in your vein.

HOW TO USE: Read and learn all preparation and usage instructions supplied by the manufacturer. Follow all instructions for proper mixing with the correct IV fluid (sterile water for injection). After mixing, do not shake the vial. Before using, check the product visually for particles or discoloration. If either is present, do not use the liquid. If any of the information is unclear, consult your pharmacist.This medication is given by slow injection into the blocked catheter, usually by a health care professional. Dosage is based on the volume inside the catheter, type of catheter, and patient's weight.If the catheter does not open within 2 hours after the first dose, a second dose may be placed. Consult the doctor.Learn how to store and discard needles and medical supplies safely. Consult your pharmacist for details.

SIDE EFFECTS: This medication usually has very few side effects. If you have any unusual effects from using this medicine, contact your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: signs of infection (e.g., fever, chills, persistent sore throat).If this medication accidentally leaks outside of the catheter when it is given, serious side effects may rarely occur. Tell your doctor immediately if you notice any of the following: bleeding at/near the catheter insertion site, other symptoms of bleeding (e.g., easy bruising, bleeding gums, pink/bloody urine, black/bloody stools, vomit that looks like coffee grounds, dizziness, lightheadedness), symptoms of a blood clot (e.g., swelling/pain in arm or near catheter).A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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