Medications and Drugs

GENERIC NAME: ALTEPLASE FOR IV CATHETERS - INJECTABLE (AL-teh-plays)

BRAND NAME(S): Cathflo Activase

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is an enzyme used to dissolve blood clots that may sometimes form within patient's IV lines (central venous access devices - CVADs). Blood clots can block the IV line and prevent other injectable drugs from being given.

HOW TO USE: Mix this product by injecting 2.2 ml of Sterile Water for Injection into the vial. Do not use a mixing solution containing a preservative (e.g., Bacteriostatic Water for Injection). Gently swirl the vial until the drug is completely dissolved. Do not shake the vial. Slight foaming or bubbles may be present. If any large bubbles are present, allow them to dissolve before drawing the solution into a syringe. If any of the mixing instructions are unclear, consult your pharmacist. Inject this medication into the blocked IV line as directed by your doctor. The dosage is usually 2 mg (1 vial). Ask your doctor or pharmacist how to use the medication correctly and follow all instructions carefully. Avoid injecting this drug too quickly or with too much force/pressure. Doing so may damage the IV line or cause the blood clot to go into the blood stream. If the IV line does not re-open within 2 hours of the first dose, a second dose may be placed into the IV line. Consult the doctor. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: No side effects are expected to occur. If side effects occur, notify your doctor immediately. Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, lightheadedness, persistent sore throat or fever. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: one-sided weakness, black stools, unusual bruising or bleeding, pain and/or swelling in the lower legs/arms/groin, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.