Disclaimer

ALTEPLASE-INJECTION, Activase (cont.)

SIDE EFFECTS: Nausea, vomiting, dizziness or mild fever may occur. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you experience: easy bruising or bleeding, skin rash, trouble breathing, rapid or abnormal heartbeat, chest pain. Immediately report any signs of bleeding to your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: bleeding disorders, high blood pressure, recent injury or surgery, liver disease, endocarditis, any allergies. Use extra caution to avoid injury and trauma while using this medication due to the increased risk of bleeding. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you may take including: "blood thinners" (e.g., warfarin), aspirin. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include fainting, vision changes, one-sided weakness, slurred speech, black stools, coughing up or vomiting blood, dizziness upon standing.

NOTES: Laboratory tests will be done frequently while using this medication to monitor its effects and to prevent side effects.

MISSED DOSE: Continued or repeated doses are usually not necessary for this medication.

STORAGE: Store in a cool area as directed and protect from light. Discard any unused medication after the expiration date on the label.


Last Editorial Review: 3/2/2005



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