GENERIC NAME: ALTEPLASE - INJECTION (AL-teh-plays)
BRAND NAME(S): Activase
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is an enzyme which works to break up and dissolve blood clots which can block arteries. It is used in the treatment of an acute heart attack or pulmonary embolism.
HOW TO USE: This medication is given by injection within 6 hours of chest pain by a health care professional. It is usually given over a two to three hour period. Continued or repeated doses are not usually required. It is important this medication be used as prescribed. It is most effective when administered as soon as possible after symptoms of a heart attack appear.
SIDE EFFECTS: Nausea, vomiting, dizziness or mild fever may occur. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you experience: easy bruising or bleeding, skin rash, trouble breathing, rapid or abnormal heartbeat, chest pain. Immediately report any signs of bleeding to your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: bleeding disorders, high blood pressure, recent injury or surgery, liver disease, endocarditis, any allergies. Use extra caution to avoid injury and trauma while using this medication due to the increased risk of bleeding. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you may take including: "blood thinners" (e.g., warfarin), aspirin. Do not start or stop any medicine without doctor or pharmacist approval.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Stroke - Learn about strokes symtoms like sudden numbness or weakness in the face, arms, or legs, confusion, vision problems, problems with walking or coordination, or severe headache.
- Heart Attack - Overview on heart attack (myocardial infarction) and heart attack symptoms including jaw pain, headache, shortness of breath, nausea, vomiting, heartburn, sweating, and more.
- Blood Clots - Learn about the causes, types, symptoms, and risk factors symptoms of blood clots such as high blood pressure, high cholesterol, diabetes, smoking, and family history. Symptoms may depend on the type of blood clot.
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