alprazolam, Xanax, Xanax XR, Niravam (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: The most common side effects of alprazolam taken at lower doses are drowsiness or lightheadedness, which probably reflect the normal actions of the drug.

Side effects of higher dosages (those used for panic attacks) include:

  • fatigue,
  • memory problems,
  • speech problems,
  • constipation, and
  • changes in appetite with resultant changes in weight.

Alprazolam can lead to addiction (dependency), especially at high doses over prolonged periods of time. Abrupt discontinuation of alprazolam after prolonged use can lead to symptoms of withdrawal such as insomnia, headaches, nausea, vomiting, lightheadedness, sweating, anxiety, and fatigue. Seizures can occur in more severe cases of withdrawal. Consequently, patients on alprazolam for extended periods of time should slowly taper the medication under a doctor's supervision rather than abruptly stopping the medication.



PREPARATIONS: Tablets: 0.25, 0.5, 1 and 2 mg. Tablets ER (extended release): 0.5, 1, 2 and 3 mg. Tablets (Orally disintegrating): 0.25, 0.5, 1 and 2 mg. Solution: 1 mg/ml

STORAGE: Alprazolam should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

DOSING: Alprazolam may be taken with or without food.

The starting dose for treating anxiety is 0.25-0.5 mg 3 to 4 times daily using immediate release tablets. The dose may be increased every 3-4 days to a maximum dose of 4 mg daily.

The starting dose for treating panic attacks is 0.5 mg 3 times daily. Doses can be increased every 3-4 days but by no more than 1 mg daily. The effective dose for preventing panic attacks may be as high as 10 mg daily for some patients. The starting dose when using extended release tablets to treat panic disorder is 0.5 mg once daily and the average dose is 3-6 mg once daily.

Medically Reviewed by a Doctor on 12/29/2014

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