Alpha-1 Antitrypsin Deficiency
What is alpha-1 antitrypsin deficiency?
Alpha-1 antitrypsin deficiency is an inherited disorder that can cause lung disease in adults and liver disease in adults and children.
What are the signs and symptoms of lung disease caused by alpha-1 antitrypsin deficiency?
The first signs and symptoms of lung disease caused by alpha-1 antitrypsin deficiency usually appear between ages 20 and 50. The earliest symptoms are:
Other signs and symptoms can include:
In rare cases, alpha-1 antitrypsin deficiency also causes a skin condition known as panniculitis, which is characterized by hardened skin with painful lumps or patches. Panniculitis varies in severity and can occur at any age.
Medically Reviewed by a Doctor on 4/1/2014
Viewers share their comments
Alpha-1 Antitrypsin Deficiency: Symptoms Question: What symptoms did you experience with alpha-1 antitrypsin deficiency? How old were you when they appeared?
Alpha 1 Antitrypsin Deficiency - Genetic Testing Question: Have you had genetic testing for alpha-1 antitrypsin deficiency? If so, what were the results?
- Allergic Skin Disorders
- Bacterial Skin Diseases
- Bites and Infestations
- Diseases of Pigment
- Fungal Skin Diseases
- Medical Anatomy and Illustrations
- Noncancerous, Precancerous & Cancerous Tumors
- Oral Health Conditions
- Papules, Scales, Plaques and Eruptions
- Scalp, Hair and Nails
- Sexually Transmitted Diseases (STDs)
- Vascular, Lymphatic and Systemic Conditions
- Viral Skin Diseases
- Additional Skin Conditions