PRECAUTIONS: Before taking allopurinol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, diabetes, hypertension, unusual diets (e.g., starvation diets). This drug may make you drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Alcohol may decrease the effectiveness of this drug. Limit alcoholic beverages. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Allopurinol passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: This drug should not be used with the following medication because very serious interactions may occur: didanosine. If you are currently using this medication, tell your doctor or pharmacist before starting allopurinol. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: certain antibiotics (amoxicillin, ampicillin), certain asthma drugs (aminophylline, theophylline), azathioprine, "blood thinners" (e.g., warfarin), chlorpropamide, cyclosporine, mercaptopurine, sulfinpyrazone, "water pills" (e.g., thiazide diuretics such as hydrochlorothiazide). Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

From the Doctors at MedicineNet.com

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