Allergy/Allergies
Medical Author: Alan Szeftel, MD, FCCP
Medical Editor: William C. Shiel Jr., MD, FACP, FACR
Introduction
In this review you will learn how allergy relates to the
immune system. You will begin understanding how and why
certain people become allergic. The most common allergic
diseases are discussed briefly in this article.
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Air Pollution and Allergies: A Connection?
Medical Author:
Alan Szeftel, MD, FCCP
Medical Editor: William
C. Shiel Jr., MD, FACP, FACR
 Does the "air we breathe" have an impact on the
rising incidence of
allergies and asthma? Hay fever was
rare in Japan before World War II. However, pollen allergy is now common and mostly affects those living in
Japanese cities and near highways. Allergic disease is also more common in highly developed
countries in North America and Europe and less common in Third World countries.
This suggests that there must be something about modern, urban life that
promotes allergy. Let us examine the impact of air pollution.
By far the most important indoor pollutant is tobacco smoke, which is
strongly associated with allergic sensitization, asthma, and other
respiratory
illnesses. Exposure to smoke results in the body's enhanced ability to produce
IgE (the allergy antibody) that attaches to allergens (e.g. pollen, dust mites
and dander). The IgE response is a key trigger of allergic reactions. Parental
smoking increases the risk of their children having many respiratory illnesses,
including bronchitis,
chronic cough, and asthma. Smoking during pregnancy and
breastfeeding results in a higher
risk for the children to develop allergic eczema (atopic
dermatitis).
Top Searched Allergy Terms:
test, symptoms, treatment, skin rash, allergic reaction, seasonal, medications, sun, mold, red bumps, dust, cat, medicine
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What does an allergy mean?
An allergy refers to an exaggerated reaction by our immune system in response to bodily contact with certain foreign substances. It is
exaggerated because these foreign substances are usually seen by the body as harmless and no response occurs in non- allergic people. Allergic people's bodies recognize the foreign substance and one part of the immune system is turned on. Allergy-producing substances are called "allergens." Examples of allergens include pollens, dust mite, molds, danders, and foods. To understand the language of allergy it is important to remember that allergens are substances that are foreign to the body and can cause an allergic reaction in certain people.
When an allergen comes in contact with the body, it
causes the immune system to develop an allergic reaction in
persons who are allergic to it. When you inappropriately
react to allergens that are normally harmless to other
people, you are having an allergic reaction and can be
referred to as allergic or atopic. Therefore, people who
are prone to allergies are said to be allergic
or "atopic."
Austrian pediatrician Clemens Pirquet (1874-1929) first
used the term allergy. He referred to both immunity that
was beneficial and to the harmful hypersensitivity
as "allergy." The word allergy is derived from the Greek
words "allos," meaning different or changed and "ergos,"
meaning work or action. Allergy roughly refers to
an "altered reaction." The word allergy was first used in
1905 to describe the adverse reactions of children who were
given repeated shots of horse serum to fight infection.
The following year, the term allergy was proposed to
explain this unexpected "changed reactivity."
Allergy Fact
- It is estimated that 50 million North Americans are
affected by allergic conditions.
- The cost of allergies in the United States is more than
$10 billion dollars yearly.
- Allergic rhinitis (nasal allergies) affects about 35 million Americans, 6 million of whom are children.
- Asthma affects 15 million Americans, 5 million of whom
are children.
- The number of cases of asthma has doubled over the last
20 years.
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Allergy
Anaphylaxis »
Introduction to anaphylaxis
Anaphylaxis refers to a rapidly developing and serious
allergic reaction that affects a number of different areas
of the body at one time. Severe anaphylactic reactions can
be fatal. Most people experience allergy
symptoms only as a minor annoyance. However, a small number of people are
susceptible to a reaction that can lead to shock or even death.
Anaphylaxis is often triggered by substances that are
injected or ingested and thereby gain access into the blood
stream. An explosive reaction involving the skin, lungs,
nose, throat, and gastrointestinal tract can then result.
Although severe cases of anaphylaxis can occur within
seconds or minutes of exposure and be fatal if untreated,
many reactions are milder and can be ended with prompt
medical therapy.
What does anaphylaxis mean?
To fully understand this term, we need
to go back almost 100 years. The story begins on
...
Read the Anaphylaxis article »
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