Allergic Cascade Symptoms, Causes, Treatment - Allergic Cascade At A Glance on MedicineNet

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Allergic Cascade (cont.)

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The Allergic Cascade At A Glance

The allergic response is usually very selective for specific allergens.
T- and B-lymphocytes play important roles in the allergic reaction.
Mast cells and basophils release a variety of chemical mediators and cytokines that cause allergic inflammation.
The immediate or "early" phase allergic reaction is subsequently followed by a more prolonged "late" phase reaction.
Histamine is an important chemical mediator that causes many of the common allergic symptoms.
Knowledge of the allergic cascade has resulted in effective treatments for allergy. Future research is aimed at finding new agents that intervene at specific levels of the allergic reaction.

Last Editorial Review: 4/1/2002

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