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alfuzosin extended-release - oral, Uroxatral (cont.)

DRUG INTERACTIONS: See also How to Use section.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: drugs to treat erectile dysfunction/pulmonary hypertension (such as sildenafil, tadalafil, vardenafil), other medications that lower blood pressure (e.g., atenolol, diltiazem).If you are also taking sildenafil and your dose is more than 25 milligrams, you can reduce your risk of fainting by taking your doses of sildenafil and alfuzosin more than 4 hours apart. Consult your doctor or pharmacist if you have any questions.Other medications can affect the removal of alfuzosin from your body, which may affect how alfuzosin works. Examples include azole antifungals (such as itraconazole, ketoconazole), boceprevir, macrolide antibiotics (such as clarithromycin), nefazodone, HIV protease inhibitors (such as ritonavir), telaprevir, telithromycin, among others.Many drugs besides alfuzosin may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using alfuzosin, report all medications you are currently using to your doctor or pharmacist.



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