DOSAGE: Alfuzosin is taken once daily, immediately after the same meal each day. Tablets should not be chewed or crushed.
- Alfuzosin should not be combined with ketoconazole (Nizoral, Extina, Xolegel, Kuric), itraconazole (Sporanox), or ritonavir (Norvir), because they increase alfuzosin blood levels by preventing the breakdown of alfuzosin by the liver.
- Combining alfuzosin with blood pressure reducing medications may increase the risk of hypotension (low blood pressure).
- PDE-5 inhibitors used primarily for erectile dysfunction (for example, vardenafil [Levitra, Staxyn], tadalafil [Cialis, Adcirca], and sildenafil [Viagra, Revatio]) add to the blood pressure lowering effects of alfuzosin and may result in orthostatic or postural hypotension.
PREGNANCY AND BREASTFEEDING SAFETY:
- Alfuzosin is not used by women; however, studies in animals have shown no evidence of fetal toxicity, even with exceedingly high doses of alfuzosin.
- Alfuzosin is not prescribed for women.
PREPARATIONS: Extended release table:, 10 mg.
STORAGE: Alfuzosin should be stored at room temperature, from 15 C to 30 C (59 F - 86 F).
How does alfuzosin (Uroxatral) work?
- Alfuzosin belongs to a class of drugs called alpha-blockers. It is used for increasing the flow of urine that is reduced by benign prostatic hypertrophy (BPH). Alpha blockers relax the muscles in the prostate gland and the neck of the bladder. This allows the urethra (the tube that conducts urine out of the bladder) to open wider so that urine flows more easily. Other medicines in this of drugs include
- Alfuzosin was approved in June 2003.
Reference: FDA Prescribing Information
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