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- What is alendronate, and how does it work (mechanism of action)?
- What brand names are available for alendronate?
- Is alendronate available as a generic drug?
- Do I need a prescription for alendronate?
- What are the uses for alendronate?
- What are the side effects of alendronate?
- What is the dosage for alendronate?
- Which drugs or supplements interact with alendronate?
- Is alendronate safe to take if I'm pregnant or breastfeeding?
- What else should I know about alendronate?
What is the dosage for alendronate?
The recommended dose for treatment of osteoporosis is 5-10 mg daily or 35-70 mg weekly. Paget's disease is treated with 40 mg once daily for six months.
Since food, other medications, and vitamins can interfere with the absorption of alendronate, they should be taken at least 30 minutes before alendronate. In order to avoid chemical irritation of the esophagus (the swallowing tube that connects the mouth with the stomach), alendronate should be taken with a full glass of plain water immediately upon arising in the morning and never chewed or sucked. It should be avoided by patients with abnormalities of the esophagus which delay esophageal emptying, such as scarring (stricture) or poor motility (achalasia). Patients should also not lie down for 30 minutes after swallowing the tablets. Those patients who are unable to remain upright for at least 30 minutes after taking alendronate should not take it.
Which drugs or supplements interact with alendronate?
Calcium supplements and antacids reduce the absorption of alendronate. Therefore, alendronate should be taken at least 30 minutes before calcium and antacids.
Quick GuideWhat Is Osteoporosis? Treatment, Symptoms, Medication
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