alemtuzumab (Campath)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: alemtuzumab




USES: Alemtuzumab is used alone for the treatment of B-cell chronic lymphocytic leukemia (B-CLL)


  • Serious, including fatal, reduction in blood cells, underdevelopment of bone marrow, autoimmune idiopathic thrombocytopenia, and autoimmune hemolytic anemia can occur in patients receiving alemtuzumab. The risk of pancytopenia is increased by single doses of alemtuzumab greater than 30 mg or doses greater than 90 mg per week.
  • Alemtuzumab may cause serious, including fatal, infusion reactions. Carefully monitor patients during infusions and withhold alemtuzumab for serious infusion reactions. Gradually increase alemtuzumab to the recommended dose at the beginning of treatment and after interruption of therapy for 7 or more days.
  • Alemtuzumab may cause serious, including fatal, bacterial, viral, fungal, and protozoan infections. Administer prophylaxis against Pneumocystis jiroveci pneumonia (PCP) and herpes virus infections.


Common side effects include:

Other side effects include:

Medically Reviewed by a Doctor on 6/15/2016
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