alefacept, Amevive

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Psoriasis Symptoms, Causes and Treatment

The most serious side effects are

Alefacept should not be used by individuals whose blood lymphocyte counts are less than 250/ml.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Powder for Injection: 15 mg/Vial for intramuscular use.

STORAGE: Alefacept should be stored at room temperature, 15 C to 30 C (59 C to 86 F).

DOSING: The recommended dose is 15 mg by intramuscular injection once weekly for 12 weeks. The treatment cycle can be repeated after a twelve week interval without treatment if the patient's T-lymphocyte counts are within the normal range.

DRUG INTERACTIONS: Alefacept suppresses the immune system. It should not be used with other drugs the also suppress the immune system because this will add to the risk of developing serious infections. Safety and efficacy of receiving live or weakened (attenuated) vaccines during alefacept treatment has not been evaluated.

PREGNANCY: Use of alefacept during pregnancy has not been evaluated.

NURSING MOTHERS: Use of alefacept by nursing mothers has not been adequately evaluated. It is not known whether alefacept is excreted in breast milk.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 6/11/2015

Quick GuidePsoriasis Types, Images, Treatments

Psoriasis Types, Images, Treatments
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