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alefacept - intramuscular, Amevive (cont.)

HOW TO USE: Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using alefacept and each time you get a refill. If you have any questions, ask your doctor or pharmacist.This medication is given by injection into a muscle as directed by your doctor, usually once weekly for 12 weeks. While you are using this medication, your doctor will order regular blood tests (usually every 2 weeks) to check for serious side effects (such as low blood counts). If serious side effects occur, your doctor may choose to delay or stop your treatment.If your doctor directs you to have more than 1 treatment period (12 weekly injections), the manufacturer recommends that you should wait at least 12 weeks between treatment periods.If you are giving the injections at home, learn all preparation and usage instructions in the product package and from your health care professional. If any of the information is unclear, consult your doctor or pharmacist.Before using, check the product visually for particles or discoloration. If either is present, do not use the liquid.Before injecting each dose, clean the injection site with rubbing alcohol. It is important to change the location of the injection site with each dose. New injections should be given at least 1 inch (2.5 centimeters) away from an old site. Do not inject into areas that are sore, bruised, red, or hard.Learn how to store and discard needles and medical supplies safely. Consult your pharmacist for details.Use this medication regularly to get the most benefit from it. If you are using this medication at home, use it on the same day each week.Tell your doctor if your condition does not improve or if it worsens.

SIDE EFFECTS: Mild pain/swelling/bleeding at the injection site and chills may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: symptoms of liver damage (e.g., severe nausea/vomiting, stomach/abdominal pain, dark urine, yellowing eyes/skin).Rarely, this medication may increase the risk of developing cancer. Tell your doctor immediately if you develop symptoms such as: unusual lumps, swollen glands, skin sores/spots that are new or change appearance.This medication can lower the body's ability to fight an infection. Tell your doctor promptly if you develop any signs of an infection such as fever, muscle aches, or persistent sore throat.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.



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