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Medications and Drugs

GENERIC NAME: albuterol and ipratropium inhaler

BRAND NAME: Combivent

DRUG CLASS AND MECHANISM: Combivent is a combination product consisting of two bronchodilators, albuterol (Proventil; Ventolin) and ipratropium (Atrovent) that is used in the treatment of chronic obstructive pulmonary disease (bronchitis and emphysema) when there is evidence of spasm (narrowing) of the airways. Bronchodilators dilate or enlarge the airways by relaxing the muscles surrounding the airways. Albuterol and ipratropium work by different mechanisms, but both cause the muscles of the airways to relax. (Ipratropium is an anticholinergic and albuterol is a sympathomimetic.)

GENERIC AVAILABLE: no

PRESCRIPTION: yes

PREPARATIONS: Combivent comes as a metered-dose aerosol inhaler delivering 90mcg of albuterol plus 18mcg of ipratropium per actuation of the inhaler.

STORAGE: The inhaler should be stored at room temperature, 15-30°C (59-86°F) and kept away from moisture.

PRESCRIBED FOR: Combivent is used in the treatment of patients with chronic obstructive pulmonary diseases such as chronic bronchitis and emphysema when they are associated with bronchospasm or narrowing of the airways due to spasm of the muscles surrounding the airways.

DOSING: The dosing of Combivent  must be individualized.

DRUG INTERACTIONS: No important drug interactions have been described with Combivent.

PREGNANCY: Please see albuterol and ipratropium.

NURSING MOTHERS: Please see albuterol and ipratropium.

SIDE EFFECTS: Please see albuterol and ipratropium.

Reference: FDA Prescribing Information


Last Editorial Review: 4/18/1999




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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Related Drugs - WebMD Health Network

albuterol and ipratropium inhaler, Combivent

What is COPD?

Chronic obstructive pulmonary disease (COPD) is comprised primarily of two related diseases - chronic bronchitis and emphysema. In both diseases, there is chronic obstruction of the flow of air through the airways and out of the lungs, and the obstruction generally is permanent and progressive over time.

Asthma also is a pulmonary disease in which there is obstruction to the flow of air out of the lungs, but unlike chronic bronchitis and emphysema, the obstruction in asthma usually is reversible. Between "attacks" of asthma the flow of air through the airways usually is good.

There are exceptions, however. In some patients with COPD the obstruction can be partially reversed by medications that enlarge or dilate the airways (bronchodilators) as with asthma. Conversely, some patients with asthma can develop permanent airway obstruction if chronic inflammation of the airways leads to scarring and narrowing of the airway...

Read the Chronic Obstructive Pulmonary Disease article »










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