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Medications and Drugs

GENERIC NAME: albuterol and ipratropium inhaler

BRAND NAME: Combivent

DRUG CLASS AND MECHANISM: Combivent is a combination product consisting of two bronchodilators, albuterol (Proventil; Ventolin) and ipratropium (Atrovent) that is used in the treatment of chronic obstructive pulmonary disease (bronchitis and emphysema) when there is evidence of spasm (narrowing) of the airways. Bronchodilators dilate or enlarge the airways by relaxing the muscles surrounding the airways. Albuterol and ipratropium work by different mechanisms, but both cause the muscles of the airways to relax. (Ipratropium is an anticholinergic and albuterol is a sympathomimetic.)

GENERIC AVAILABLE: no

PRESCRIPTION: yes

PREPARATIONS: Combivent comes as a metered-dose aerosol inhaler delivering 90mcg of albuterol plus 18mcg of ipratropium per actuation of the inhaler.

STORAGE: The inhaler should be stored at room temperature, 15-30°C (59-86°F) and kept away from moisture.

PRESCRIBED FOR: Combivent is used in the treatment of patients with chronic obstructive pulmonary diseases such as chronic bronchitis and emphysema when they are associated with bronchospasm or narrowing of the airways due to spasm of the muscles surrounding the airways.

DOSING: The dosing of Combivent  must be individualized.

DRUG INTERACTIONS: No important drug interactions have been described with Combivent.

PREGNANCY: Please see albuterol and ipratropium.

NURSING MOTHERS: Please see albuterol and ipratropium.

SIDE EFFECTS: Please see albuterol and ipratropium.

Reference: FDA Prescribing Information


Last Editorial Review: 4/18/1999




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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albuterol and ipratropium inhaler, Combivent

What Is Exercise-Induced Asthma?

Like it sounds, exercise-induced asthma is asthma that is triggered by vigorous or prolonged exercise or physical exertion. Most people with chronic asthma experience symptoms of asthma during exercise. However, there are many people without chronic asthma who develop symptoms only during exercise.

Why Does Exercise Induce Asthma?

During normal breathing, the air we take in is first warmed and moistened by the nasal passages. Because people tend to breathe through their mouths when they exercise, they are inhaling colder and drier air.

In exercise-induced asthma, the muscle bands around the airways are sensitive to these changes in temperature and humidity and react by contracting, which narrows the airway. This results in symptoms of exercised-induced asthma, which include:

  • Coughing with asthma
  • Tightening of the chest
  • W...

Read the Exercise-Induced Asthma article »










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