albuterol, Ventolin HFA, Proventil-HFA, Vospire ER, ProAir HFA (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
STORAGE: Albuterol should be stored at room temperature, 59 F - 86 F (15 C - 30 C). The canister should be kept away from heat or flame and not punctured.
DOSING: The usual dose for prevention of bronchospasm is 1-2 inhalations every 4-6 hours by aerosol. The dose for exercise induced bronchospasm is 2 inhalations 15 minutes prior to exercise. The usual nebulizer dose is 0.63 mg, 1.25 mg or 2.5 mg 3-4 times a day. The recommended dosing for tablets or syrup is 2 or 4 mg given 3 or 4 times daily and the dose of extended release tablets is 4 or 8 mg every 12 hours.
DRUG INTERACTIONS: Tricyclic antidepressants [for example, amitriptyline (Elavil, Endep), monoamine oxidase inhibitors (for example, tranylcypromine) should not be combined with albuterol because of their additive effects on the vascular system (increased blood pressure, heart rate, etc.). A period of two weeks should elapse between treatment with albuterol and tricyclic antidepressants or monoamine oxidase inhibitors.
Use of albuterol with other stimulant medications is discouraged because of their combined effects on heart rate, blood pressure, and the potential for causing chest pain in patients with underlying coronary heart disease.
Beta-blockers [for example, propranolol (Inderal, Inderal LA) block the effect of albuterol and may induce bronchospasm in asthmatics. Albuterol may cause hypokalemia (low potassium). Therefore, combining albuterol with loop diuretics [for example, furosemide (Lasix)] may increase the likelihood of hypokalemia.
Medically Reviewed by a Doctor on 1/27/2015
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