albuterol (Accuneb, [Ventolin and Proventil have been discontinued]) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREPARATIONS:

  • Inhalation Solution: 0.63, 1.25, and 2.5 mg/3 ml; 2.5 mg/0.5 ml.

DRUG INTERACTIONS:

  • Tricyclic antidepressants, for example, amitriptyline (Elavil, Endep), and monoamine oxidase inhibitors (MAOIs), for example, tranylcypromine, should not be combined with albuterol sulfate because of their additive effects on the vascular system (increased blood pressure, heart rate, etc.). A period of two weeks should elapse between treatment with albuterol sulphate and tricyclic antidepressants or monoamine oxidase inhibitors.
  • Use of albuterol sulphate with other stimulant medications is discouraged because of their combined effects on heart rate, blood pressure, and the potential for causing chest pain in patients with underlying coronary heart disease.
  • Beta-blockers, for example, propranolol (Inderal, Inderal LA), block the effect of albuterol sulphate and may induce bronchospasm in asthmatics.
  • Albuterol sulphate may cause hypokalemia (low potassium). Therefore, combining albuterol sulphate with loop diuretics, for example, furosemide (Lasix) may increase the likelihood of hypokalemia.

PREGNANCY AND BREASTFEEDING SAFETY:

  • Albuterol sulphate inhalation solution is used for treating children.
  • There are no adequate studies of albuterol sulphate use during pregnancy. Some reports indicate that albuterol sulphate may cause congenital defects when used during pregnancy.
  • It's not known whether albuterol sulphate is excreted in breast milk.
Medically Reviewed by a Doctor on 4/7/2016


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