DOSAGE: The dosing of albendazole depends on which parasitic infection is being treated. When treating young children, tablets may be crushed or chewed and swallowed with a drink of water. Patients are advised to take albendazole with food.
Hydatid disease: Patients are treated with albendazole for 28 days followed by a 14 day albendazole free interval, for a total of 3 cycles. Dosing is based on patient weight as follows:
- = 60 kg: 400 mg twice daily with meals
- < 60 kg: 15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose is 800 mg)
Neurocysticercosis: Treatment duration is 8 to 30 days. Patients are generally prescribed concurrent anticonvulsant (anti-seizure) and corticosteroid therapy during the first week. Dosing is based on patient weight as follows:
- ≥ 60 kg: 400 mg twice daily with meals
- < 60 kg: 15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)
Treatment of pediatric patients: doses vary; dose should be determined by a physician with experience treating children with this drug.
DRUG INTERACTIONS: Grapefruit juice may increase in blood levels of albendazole when administered concurrently. Fosphenytoin (Cerebyx) and phenytoin (Dilantin) decrease levels of albendazole by increasing its breakdown.
PREGNANCY AND BREASTFEEDING SAFETY: There are no adequate clinical trials of albendazole administration during pregnancy. Albendazole should only be used during pregnancy if the potential benefit of treatment justifies the potential risk to the fetus. Albendazole has been classified FDA as pregnancy risk category C.
It is not known if albendazole is excreted in human milk. Due to the lack of safety data, albendazole should be used cautiously during breastfeeding.
Quick GuideSymptoms of Mono: Infectious Mononucleosis Treatment
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