Adlyxin (lixisenatide)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is lixisenatide, and how does it work?

  • Lixisenatide is an injectable drug that reduces the level of sugar (glucose) in the blood. It is used for the treatment type 2 diabetes and is similar to
  • Lixisenatide belongs in a class of drugs called incretin mimetics because these drugs mimic the effects of incretins. Incretins, such as human-glucagon-like peptide-1 (GLP-1), are hormones that are produced and released into the blood by the intestine in response to food. GLP-1 increases the secretion of insulin from the pancreas, slows absorption of glucose from the gut, and reduces the action of glucagon. (Glucagon is a hormone that increases glucose production by the liver.) All three of these actions reduce levels of glucose in the blood. In addition, GLP-1 reduces appetite. Lixisenatide is a synthetic (man-made) hormone that resembles and acts like GLP-1. In studies, lixisenatide treated patients achieved lower blood glucose levels and experienced weight loss.

What brand names are available for lixisenatide?

  • Adlyxin is the brand name available for lixisenatide available in the US.

Is lixisenatide available as a generic drug?

  • No

Do I need a prescription for lixisenatide?

  • Yes

What are the uses for lixisenatide?

What are the side effects of lixisenatide?

Common side effects of include:

Other possible side effects of include:

Possible serious side effects of include:

Medically Reviewed by a Doctor on 1/9/2017

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