Adderall vs. Concerta

  • Medical Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Can I become addicted to these drugs?

Adderall can become physically addictive and cause withdrawal symptoms when the drug is stopped, whereas these problems aren't typically reported with Concerta or Ritalin. Methylphenidate, however, can be habit-forming and should be tapered off rather than stopped abruptly.Adderall usually is taken once or twice a day with 4-6 hours between doses. The recommended dose is 2.5 to 60 mg daily, depending on the patient's age and condition. Adderall XR (the extended-release version of the drug) is taken once daily in doses of 5 to 40 mg. The entire contents of the Adderall XR capsules can be mixed with food. Avoid late evening doses for both Adderall and Adderall XR to prevent insomnia.

Methylphenidate may be given once, twice, or three times daily, depending on formulation, at dose levels of 18-72 mg total in the day.

Which drugs interact with Adderall and Concerta?

Don't take either Adderall or Concerta with monamine oxidase inhibitors (MAOIs). The danger of an extreme high blood pressure reaction to combining MAOIs and either medication is so great, people should avoid taking Adderall or Concerta until two weeks have passed since the last MAOI dose.

High blood pressure is exacerbated by both methylphenidate and the amphetamine and dextroamphetamine in Adderall, therefore; either medication may render blood pressure medications less effective.

Caffeine is also a stimulant, and can adversely magnify effects of both Adderall and Concerta. Coffee and other caffeine-containing beverages should be avoided while taking either medication.

Antacids can also increase the effect of Adderall by allowing the body to absorb more of the amphetamine combination, so avoid antacids while taking Adderall.

Medically Reviewed by a Doctor on 2/7/2017

Quick GuideWhat's Your Biggest Fear? Phobias

What's Your Biggest Fear? Phobias
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Depression Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors