adapalene, Differin (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREGNANCY: Only very small amounts of adapalene are absorbed through skin and into the body. However, there are no adequate studies in pregnant women.

NURSING MOTHERS: It is not known whether adapalene is excreted in breast milk.

SIDE EFFECTS: The most common side effects of adapalene are irritation, redness, dryness, and itching of the skin as well as flares of acne. Most of these side effects lessen with continued use; however, if they are bothersome, decreasing the frequency with which adapalene is applied may reduce these side effects.

Adapalene may increase the sensitivity of the skin to sun and lead to sunburn. Excessive sun exposure should be avoided, and sunscreens should be used over the treated areas if exposure to the sun cannot be avoided. Adapalene should not be applied to sunburned skin, cuts, eyes, nose, or lips.

Reference: FDA Prescribing Information

Last Editorial Review: 12/14/2010

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