adalimumab, Humira (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Adalimumab is used for reducing the signs and symptoms of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, juvenile idiopathic arthritis, and Crohn's disease. It also slows the progression (destruction of the joints) and improves physical function in moderate to severe rheumatoid arthritis. Adalimumab can be used alone or in combination with methotrexate (Rheumatrex, Trexall) or other DMARDs.

SIDE EFFECTS: The most common side effects are:

Adalimumab may cause swelling, redness, pain and itching at the site of injection. Adalimumab suppresses the immune system and is therefore associated with minor infections of the urinary tract, respiratory tract, and sinuses. Like other drugs that block TNF, use of adalimumab also has been associated with serious infections such as tuberculosis, sepsis (bacteria in the blood) and fungal infections. Individuals with active infections should not be treated with adalimumab. Adalimumab also may worsen the symptoms of diseases of the nervous system. In studies some patients who used adalimumab or other TNF blocking drugs developed cancer. Since patients with rheumatoid arthritis have a higher rate of cancers than the general population, the connection between cancer and use of adalimumab is unclear.

Medically Reviewed by a Doctor on 4/7/2015

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