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February 10, 2012

Actinic Keratosis Glossary of Terms

The following are health and medical definitions of terms that appear in the Actinic Keratosis article.

5-fluorouracil: An anticancer drug, See: Fluorouracil.

5-FU: 5-fluorouracil, an anticancer drug. See: Fluorouracil.

Actinic: Referring to the ultraviolet (UV) rays from sunlight and UV lamps. Sunburn is an actinic burn. An actinic keratosis is a skin lesion that is the consequence of chronic sun exposure. From the Greek "aktis" meaning "ray."

Actinic keratosis: A small rough spot on skin chronically exposed to the sun, precancerous, can develop into a skin cancer called squamous cell carcinoma, a process that typically takes years. Actinic keratoses occur most frequently in fair-skinned people. Common locations are the face, scalp, back of the neck, upper chest, forearm and back of the hand.
See the entire definition of Actinic keratosis

Adjacent: Lying nearby. Related terms include superjacent, subjacent, and circumjacent. From ad-, near + the Latin jacere, to lie = to lie near.

ALA: 1. Alpha-linolenic acid 2.Aminolevulinic acid, a naturally occurring chemical in the body that is converted to protoporphryn IX, a light-sensitive compound. Aminolevulinic acid has been used in the photodynamic therapy of skin precancer and cancer.

Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Bridge: A set of one or more false teeth supported by a metal framework, used to replace one or more missing teeth.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
See the entire definition of Cancer

Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast, colon, liver, lung, prostate, and stomach.

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane.
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Cheilitis: Inflammation of the lips or of a lip. Cheilitis can also be spelled chilitis.
See the entire definition of Cheilitis

Chest: The area of the body located between the neck and the abdomen. The chest contains the lungs, the heart and part of the aorta. The walls of the chest are supported by the dorsal vertebrae, the ribs, and the sternum.
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Cryosurgery: Treatment performed with an instrument that freezes and destroys abnormal tissue.
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Cutaneous: Relating to the skin. As, for example, in cutaneous allodynia, a cutaneous papilloma, and cutaneous syndactyly. From the Latin cutis meaning skin.

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Hypertrophic: Exhibiting hypertrophy (enlargement or overgrowth of an organ or part of the body due to increased size of the constituent cells), as in hypertrophic cardiomyopathy.

Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever. Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.

Immune: Protected against infection. The Latin immunis means free, exempt.

Inflammation: A basic way in which the body reacts to infection, irritation or other injury, the key feature being redness, warmth, swelling and pain. Inflammation is now recognized as a type of nonspecific immune response.
See the entire definition of Inflammation

Keratosis: A localized horny overgrowth of the upper layer of skin such as a callus or wart. Among the common forms of keratosis are actinic keratosis and senile keratosis.

Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
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Liquid nitrogen: Nitrogen in a liquid state. Liquid nitrogen is supercool -- about 200 degrees Celsius (320 degrees Fahrenheit) below zero -- and is used for cryopreservation, cryosurgery, and cryomedicine.
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Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body.
See the entire definition of Malignant

Metastasis: 1. The process by which cancer spreads from the place at which it first arose as a primary tumor to distant locations in the body.
2. The cancer resulting from the spread of the primary tumor. For example, someone with melanoma may have a metastasis in their brain. And a person with colon cancer may, fortunately, show no metastases.
See the entire definition of Metastasis

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.

Nitrogen: Element number 7, a colorless, odorless, tasteless gas that is biologically important. Nitrogen is a constituent of protein and nucleic acids and is present in all living cells. Nitrogen does not support respiration and is fatal if breathed alone, because of the lack of oxygen. Nitrogen is soluble in the blood and body fluids and, when released as bubbles of gas, can have serious or even fatal consequences.
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Nose: The external midline projection from the face.
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NSAID: Nonsteroidal anti-inflammatory drug. NSAIDs are commonly prescribed for the inflammation of arthritis and other body tissues, such as in tendinitis and bursitis. Examples of NSAIDs include aspirin, indomethacin (Indocin), ibuprofen (Motrin), naproxen (Naprosyn), piroxicam (Feldene), and nabumetone (Relafen).
See the entire definition of NSAID

Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye, ear, heart, lungs, and liver.

Photodynamic therapy: A form of cancer treatment using an photosensitizing agent administered intravenously which concentrates selectively in tumor cells, followed by exposure of the tumor tissue to a special red laser light, in order to destroy as much of the tumor as possible.
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Precancerous: Pertaining to something that is not yet overtly cancerous, but appears to be on its way to becoming a cancer. Synonymous with premalignant.

Premalignant: Pertaining to tissue that is not yet malignant, but is poised to become malignant. Appropriate clinical and laboratory studies are designed to detect premalignant tissue while it is still in a premalignant stages. A large battery of techniques are generally available to remove or kill the tissue, thereby preventing the development of cancer. The proper treatment method depends on the particular premalignant tissue involved. Following are a few examples of premalignant growths:
See the entire definition of Premalignant

Psoriasis: A reddish, scaly rash often located over the surfaces of the elbows, knees, scalp, and around or in the ears, navel, genitals or buttocks. Psoriasis is an autoimmune disease that is mediated by T lymphocytes. It is also a very common disease, Chronic plaque psoriasis affects approximately 2% of people around the world. About 10-15% of patients with psoriasis develop joint inflammation (inflammatory arthritis). Treatment options include topical steroid creams, tar soap preparations, and exposure to ultraviolet light.
See the entire definition of Psoriasis

PUVA: PUVA stands for psoralen (P) and ultraviolet A (UVA) therapy in which the patient is exposed first to psoralens (drugs containing chemicals that react with ultraviolet light) and then to UVA light.
See the entire definition of PUVA

Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.

Scaling: Abnormal shedding or accumulation of an upper layer of skin (the stratum corneum).

Solar keratosis: Synonymous with actinic keratosis. See: Keratosis, actinic.

Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat. 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Squamous cell carcinoma: Cancer that begins in squamous cells -- thin, flat cells that look under the microscope like fish scales. Squamous cells are found in the tissue that forms the surface of the skin, the lining of hollow organs of the body, and the passages of the respiratory and digestive tracts. Squamous cell carcinomas may arise in any of these tissues.
See the entire definition of Squamous cell carcinoma

Stage: As regards cancer, the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging.

Superficial: In anatomy, on the surface or shallow. As opposed to deep. The skin is superficial to the muscles. The cornea is on the superficial surface of the eye.
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
See the entire definition of Surgery

Therapy: The treatment of disease.
See the entire definition of Therapy

Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.

Transplant: The grafting of a tissue from one place to another, just as in botany a bud from one plant might be grafted onto the stem of another. The transplanting of tissue can be from one part of the patient to another (autologous transplantation), as in the case of a skin graft using the patient's own skin; or from one patient to another (allogenic transplantation), as in the case of transplanting a donor kidney into a recipient.

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Ultraviolet radiation: Invisible rays that are part of the energy that comes from the sun. Ultraviolet radiation can burn the skin and cause skin cancer.
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    • Rash
      • The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
    • Psoriasis
      • Psoriasis is a long-term skin condition that may cause large plaques of red, raised skin, flakes of dry skin, and skin scales. There are several types of psoriasis, including psoriasis vulgaris, guttate psoriasis, inverse psoriasis, and pustular psoriasis. Symptoms vary depending on the type of psoriasis the patient has. Treatment of psoriasis may include creams, lotions, oral medications, injections and infusions of biologics, and light therapy. There is no cure for psoriasis.
    • Skin Cancer
      • Skin cancer is the most common form of cancer in humans. There are three main types of skin cancer; basal cell carcinoma and squamous cell carcinoma (the nonmelanoma skin cancers), and melanoma.
    • Sunburn (Sun Poisoning)
      • Sunburn is caused by overexposure to UV radiation from the sun. UV rays can also damage the eyes. Repeated overexposure to UV rays also increases the risk for scarring, freckles, wrinkles, and dry skin. Symptoms of sunburn include painful, red, tender, and hot skin. The skin may blister, swell, and peel. Sun poisoning (severe sunburn) include nausea, fever, chills, rapid pulse, dizziness and more. Treatment for sunburn depends upon the severity. Sun protection and sunscreen for an individual's skin type is recommended to decrease the chance of sunburn.
    • Wrinkles
      • Wrinkles, whether they be fine line or deep furrows, typically appear on areas of the body that receive a high amount of exposure to the sun. Smoking, light skin type, hairstyle, the way you dress, your occupational and recreational habits, and heredity are all factors that promote wrinkling. Medical treatments for wrinkles include antioxidants, moisturizers, alpha-hydroxy acids, and vitamin A acid. Cosmetic procedures that treat wrinkles include dermabrasion, microdermabrasion, glycolic acid peels, laser resurfacing, Botox, and fillers.
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Actinic Keratosis

Psoriasis facts

  • Psoriasis is a chronic inflammatory skin disease.
  • Psoriasis has no known cause.
  • The tendency toward developing psoriasis is inherited in genes.
  • Psoriasis is not contagious.
  • Psoriasis gets better and worse spontaneously and can have periodic remissions (clear skin).
  • Psoriasis is controllable with medication.
  • Psoriasis is currently not curable.
  • There are many promising therapies, including newer biologic drugs.
  • Future research for psoriasis is promising.

What is psoriasis?

Psoriasis is a noncontagious skin condition that produces red, dry plaques of thickened skin. The dry flakes and skin scales are thought to result from the rapid proliferation of skin cells that is triggered by abnormal lymphocytes from the blood . Psoriasis commonly affects the skin of the elbows, knees, and scalp.

Some people have such mild ps...

Read the Psoriasis article »




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