Acquired Immunodeficiency Syndrome Glossary of Terms

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Abstinence: The voluntary self-denial of food, drink, or sex. Today, abstinence most commonly refers to denial of one's sexual activity.

Acquired: Anything that is not present at birth but develops some time later. In medicine, the word "acquired" implies "new" or "added." An acquired condition is "new" in the sense that it is not genetic (inherited) and "added" in the sense that was not present at birth.
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Acquired immunodeficiency syndrome: AIDS. AIDS is a disease due to infection with the human immunodeficiency virus (HIV). Also referred to as acquired immunodeficiency disease.

Antiretroviral: An agent or process effective against a retrovirus. For example, a drug to treat HIV.

Artery: A vessel that carries blood high in oxygen content away from the heart to the farthest reaches of the body. Since blood in arteries is usually full of oxygen, the hemoglobin in the red blood cells is oxygenated. The resultant form of hemoglobin (oxyhemoglobin) is what makes arterial blood look bright red.
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Assay: An assay is an analysis done to determine:

1. The presence of a substance and the amount of that substance. Thus, an assay may be done for example to determine the level of thyroid hormones in the blood of a person suspected of being hypothyroid (or hyperthyroid).
2. The biological or pharmacological potency of a drug. For example, an assay may be done of a vaccine to determine its potency.

AZT: Zidovudine (formerly called azidothymidine [abbreviated AZT]), a drug used against human immunodeficiency virus (HIV), the virus that causes AIDS. The brand name is Retrovir.
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterial: Of or pertaining to bacteria. For example, a bacterial lung infection.

Bacterium: The singular of bacteria.

Brain: That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."

Breastfeeding: Feeding a child human breast milk. According to the American Academy of Pediatrics, human breast milk is preferred for all infants. This includes even premature and sick babies, with rare exceptions. It is the food least likely to cause allergic reactions; it is inexpensive; it is readily available at any hour of the day or night; babies accept the taste readily; and the antibodies in breast milk can help a baby resist infections.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Candidiasis: Overgrowth of the C. albicans yeast in the gastrointestinal tract, or infection of other body areas with this yeast. Vaginal yeast infections, some forms of diaper rash and other skin rashes that emerge in moist, warm areas of skin, and thrush (a condition characterized by patches of white inside the mouth and/or throat) are all forms of yeast infection. Candidiasis tends to develop when the normal balance of bacteria (flora) in the area is upset, as can occur with antibiotic use. Prevention measures include the use of probiotics and in some cases dietary changes. Treatment is via antifungal medications. Candidiasis is usually a minor and easily addressed problem, but can be more serious for those with immune-system disorders, such as AIDS.

CCR5: A chemokine receptor found on monocytes and lymphocytes that serves as the coreceptor for HIV. HIV strains that use this coreceptor are referred to as R5 viruses. Polymorphisms in the coding and non-coding regions of the CCR5 gene influence the natural history of HIV infection. CCR5 (or CCCR5) stands for the CC chemokine receptor 5.

CDC: The Centers for Disease Control and Prevention, the US agency charged with tracking and investigating public health trends. The stated mission of the CDC is "To promote health and quality of life by preventing and controlling disease, injury, and disability." The CDC is a part of the U.S. Public Health Services (PHS) under the Department of Health and Human Services (HHS).
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane.
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Centers for Disease Control and Prevention: The US agency charged with tracking and investigating public health trends. The stated mission of the Centers for Disease Control and Prevention, commonly called the CDC, is "To promote health and quality of life by preventing and controlling disease, injury, and disability."
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Cervical: Having to do with any kind of neck including the neck on which the head is perched and the neck of the uterus. The word "cervix" in Latin means "neck". That is why cervical vertebrae and cervical cancer involve quite disparate parts of the anatomy joined only by the meaning of the word "cervix".

Chlamydia: A type of bacteria one species of which causes an infection very similar to gonorrhea in the way that it is spread, the symptoms it produces, and the long-term consequences.
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Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Chronic disease: A disease that persists for a long time. A chronic disease is one lasting 3 months or more, by the definition of the U.S. National Center for Health Statistics. Chronic diseases generally cannot be prevented by vaccines or cured by medication, nor do they just disappear. Eighty-eight percent of Americans over 65 years of age have at least one chronic health condition (as of 1998). Health damaging behaviors - particularly tobacco use, lack of physical activity, and poor eating habits - are major contributors to the leading chronic diseases.
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Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
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Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.

Cryptococcosis: Infection with fungus (usually in a yeast form) from the genus Cryptococcus, such as Cryptococcus neoformans or Cryptococcus gattii. Cryptococcosis is generally a rare condition, but about 7%-15% of people with AIDS may acquire the infection. Infection is rare but can also occur in people with a normally functioning immune system. The infection can manifest as pneumonia with spread to the brain and other organs. Cryptococcal meningoencephalitis is fatal if not treated. Amphotericin B and other antifungal medications are used to treat cryptococcosis.

Cryptosporidiosis: An intestinal infection characterized by diarrhea caused by a microscopic parasite, Cryptosporidium parvum. The parasite lives in the small intestine of humans and animals who pass it in their feces. The parasite is protected by an outer shell that allows it to survive outside the body for long periods of time and makes it resistant to chlorine disinfection. Both the disease and the parasite are popularly known as "Crypto." The disease is also called cryptosporidium enteritis.
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Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma.
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Dementia: Significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning.
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Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea: A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation. The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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DNA: Deoxyribonucleic acid. One of two types of molecules that encode genetic information. (The other is RNA. In humans DNA is the genetic material; RNA is transcribed from it. In some other organisms, RNA is the genetic material and, in reverse fashion, the DNA is transcribed from it.)
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Drug resistance: The ability of bacteria and other microorganisms to withstand a drug to which they were once sensitive and were once slowed in growth or killed outright.

Encephalopathy: Disease, damage, or malfunction of the brain. In general, encephalopathy is manifested by an altered mental state that is sometimes accompanied by physical changes. Although numerous causes of encephalopathy are known, the majority of cases arise from infection, liver damage, anoxia, or kidney failure. The term encephalopathy is very broad and, in most cases, is preceded by various terms that describe the reason, cause, or special conditions of the patient that leads to brain malfunction. For example, anoxic encephalopathy means brain damage due to lack of oxygen, and hepatic encephalopathy means brain malfunction due to liver disease. Depending upon the cause and severity of the condition, symptoms may range from mild alterations in mental status to severe and potentially fatal manifestations such as dementia, seizures, and coma.

Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions, converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
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Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.

Essential: 1. Something that cannot be done without.
2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid.
3. Idiopathic. As in essential hypertension. "Essential" is a hallowed term meaning "We don't know the cause."

Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Feces: The medical and scientific term for the "excrement discharged from the intestines."
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Finger stick: A procedure in which a finger is pricked with a lancet to obtain a small quantity of capillary blood for testing. Also called a finger prick.

Fungal: Pertaining to a fungus. For example, a fungal skin infection.

Fungus: A single-celled or multicellular organism. Fungi can be true pathogens (such as histoplasmosis and coccidioidomycosis) that cause infections in healthy persons or they can be opportunistic pathogens (such as aspergillosis, candidiasis, and cryptococcosis) that cause infections in immunocompromised persons (including cancer patients, transplant recipients, and persons with AIDS). An example of a common fungus is the yeast organism which causes thrush and diaper rash (diaper dermatitis). Fungi are also used for the development of antibiotics, antitoxins, and other drugs used to control various human diseases.

Genes: The basic biological units of heredity. Segments of deoxyribonucleic acid (DNA) needed to contribute to a function.
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Genetic: Having to do with genes and genetic information.

Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)

Gestation: Period of time from conception to birth.

Gonorrhea: A sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. Although gonorrhea is known primarily as a sexually transmitted infection (STI), it is not exclusively so, but can also be transmitted to the newborn during the birthing process.
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HAART: Stands for highly active antiretroviral therapy. Treatment with a very potent drug "cocktail" to suppress the growth of HIV, the retrovirus responsible for AIDS.

Hepatitis: Inflammation of the liver from any cause.
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Hepatitis B: Inflammation of the liver due to the hepatitis B virus (HBV), once thought to be passed only through blood products. It is now known that hepatitis B can also be transmitted via needle sticks, body piercing and tattooing using un sterilized instruments, the dialysis process, sexual and even less intimate close contact, and childbirth. Symptoms include fatigue, jaundice, nausea, vomiting, dark urine, light stools. Diagnosis is by blood test. Treatment is via anti-viral drugs and/or hepatitis B immunoglobulin (HBIG).
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Herpes: A family of viruses. Herpes also refers to infection with one of the human herpesviruses, especially herpes simplex types 1 and 2.
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Heterosexual: A person sexually attracted to persons of the opposite sex. Or a person who has sexual relations with the opposite sex. Colloquially known as "straight."
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Histoplasmosis: A disease caused by the fungus Histoplasma capsulatum. Most people with histoplasmosis have no symptoms. However, histoplasma can cause acute or chronic lung disease and progressive disseminated histoplasmosis affecting a number of organs. It can be fatal if untreated.
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HIV: Acronym for the Human Immunodeficiency Virus, the cause of AIDS (acquired immunodeficiency syndrome). HIV has also been called the human lymphotropic virus type III, the lymphadenopathy-associated virus and the lymphadenopathy virus. No matter what name is applied, it is a retrovirus. (A retrovirus has an RNA genome and a reverse transcriptase enzyme. Using the reverse transcriptase, the virus uses its RNA as a template for making complementary DNA which can integrate into the DNA of the host organism).
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HIV test: A test for the human immunodeficiency virus, the cause of AIDS. HIV tests are designed to detect antibodies to the HIV virus or the HIV virus itself.
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Homosexual: A person sexually attracted to persons of the same sex. Homosexuals include males (gays) and females (lesbians).
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Human immunodeficiency virus: HIV, the cause of AIDS. HIV has also been called the human lymphotropic virus type III, the lymphadenopathy-associated virus and the lymphadenopathy virus. No matter what name is applied, it is a retrovirus. (A retrovirus has an RNA genome and a reverse transcriptase enzyme. Using the reverse transcriptase, the virus uses its RNA as a template for making complementary DNA which can integrate into the DNA of the host organism). Although the American research Robert Gallo at the National Institutes of Health believed he was the first to find HIV, it is now generally accepted that the French physician Luc Montagnier (1932-) and his team at the Pasteur Institute discovered HIV in 1983- 84.

Immune: Protected against infection. The Latin immunis means free, exempt.

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Immunodeficiency: Inability to mount a normal immune response. Immunodeficiency can be due to a genetic disease or acquired as in AIDS due to HIV.

Indirect immunofluorescence assay: A laboratory test used to detect antibodies in serum or other body fluid. The specific antibodies are labeled with a compound that makes them glow an apple-green color when observed microscopically under ultraviolet light.

Infant: A child up to 2 years (24 months) of age.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Infectious mononucleosis: A specific viral infection (with the Epstein-Barr virus) in which there is an increase of white blood cells that are mononuclear (with a single nucleus) "Mono" and "kissing disease" are popular terms for this very common illness caused by the Epstein-Barr virus (EBV). By the time most people reach adulthood, an antibody against EBV can be detected in their blood meaning they have been infected with EBV. The illness is less severe in young children. The infection can be spread by saliva. The incubation period for infectious mononucleosis is 4 to 8 weeks. Symptoms include fever, fatigue, sore throat, and swollen lymph glands. "Mono" can cause liver inflammation (hepatitis) and spleen enlargement. Vigorous contact sports should be avoided to prevent spleen rupture.

Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.

Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.

Intractable: Unstoppable. For example, intractable diarrhea or intractable pain.

Kaposi sarcoma: A relatively rare type of skin malignancy that tends to afflict elderly people or, especially, those with an abnormal immune system as in AIDS. Kaposi sarcoma is a highly vascular ("angioblastic") tumor of the skin characterized by soft purplish plaques and papules that form nodules which typically start on the feet and ankles and then slowly spread across the skin of the legs, hands and arms. In AIDS patients, these tumors can also develop internally and cause severe internal bleeding.
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Labor: Childbirth, the aptly-named experience of delivering the baby and placenta from the uterus to the vagina to the outside world. There are two stages of labor. During the first stage (called the stage of dilatation), the cervix dilates fully to a diameter of about 10 cm. In the second stage (called the stage of expulsion), the baby moves out through the cervix and vagina to be born.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."

Latent: Hidden, dormant, inactive.
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Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.

Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy, radiation, surgery, or medication, depending on the age of the patient and type of tumor.

Maternal: 1. Pertaining to the mother as, for example, the maternal mortality rate. 2. Related through the mother as, for example, the maternal grandparents. 3. Inherited from the mother as, for example, the maternal X chromosome.

Membrane: A very thin layer of tissue that covers a surface.

Meningitis: Inflammation of the meninges, usually due to a bacterial infection but sometimes from viral, protozoan, or other causes (in some cases the cause cannot be determined).
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Mononucleosis: Infection with the Epstein-Barr virus (EBV, human herpesvirus 4, HHV-4) in which there is an increase of white blood cells that have a single nucleus (monocytes). The infection can be spread by saliva. Its incubation period is four to eight weeks. Symptoms include fever, fatigue, sore throat, and swollen lymph glands. Mononucleosis can cause liver inflammation (hepatitis) and spleen enlargement; vigorous contact sports should be avoided to prevent spleen rupture. It is less severe in young children.
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Mucous: Pertaining to mucus, a thick fluid produced by the lining of some tissues of the body.
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Multifocal: Having to do with two or more foci or arising from two or more places. For example, aortic aneurysm disease is often multifocal and needs total aortic screening for diagnosis.

Mycobacterium: A large family of bacteria that have unusually waxy cell walls that are resistant to digestion.
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Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.

Needle stick: See: Needlestick injury.

Neurological: Having to do with the nerves or the nervous system.

Noncompliance: The failure or refusal to comply: the failure or refusal to conform and adapt one's actions to a rule or to necessity.
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Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye, ear, heart, lungs, and liver.

Pandemic: An epidemic (a sudden outbreak) that becomes very widespread and affects a whole region, a continent, or the world.
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Parasite: An organism that lives in or on and takes its nourishment from another organism. A parasite cannot live independently.
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Pneumocystis: Pneumocystis jiroveci (previously classified as Pneumocystis carinii), the fungus that causes pneumocystis pneumonia (PCP). Pneumocystis jiroveci is found worldwide, in humans and animals. Serologic evidence indicates that most healthy children have been exposed to it by age 3 to 4. Pneumocystis pneumonia (PCP) occurs in immunosuppressed individuals and in premature, malnourished infants.
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Pneumocystis jiroveci: See: Pneumocystis.

Pneumonia: Inflammation of one or both lungs with consolidation. Pneumonia is frequently but not always due to infection. The infection may be bacterial, viral, fungal or parasitic. Symptoms may include fever, chills, cough with sputum production, chest pain, and shortness of breath.

Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pregnant: The state of carrying a developing fetus within the body.
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Prognosis: 1. The expected course of a disease.
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient. His prognosis is grim, for example, while hers is good.
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Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.

Progressive multifocal leukoencephalopathy: A rapidly progressive, often fatal viral infection of the brain. Commonly abbreviated as PML.
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Prophylaxis: A measure taken for the prevention of a disease or condition.
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Protease: An enzyme that can split a protein into peptides (from which the protein was originally created).

Proteins: Large molecules composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.

Regimen: With the accent on the first syllable (reg as in Reggie Jackson), a regimen is a plan, a regulated course such as a diet, exercise or treatment, designed to give a good result. A low-salt diet is a regimen.

Reproduction: The production of offspring. Reproduction need not be sexual. Yeast can reproduce by budding.

Resistance: Opposition to something, or the ability to withstand it. For example, some forms of staphylococcus are resistant to treatment with antibiotics.

Respiratory: Having to do with respiration, the exchange of oxygen and carbon dioxide. From the Latin re- (again) + spirare (to breathe) = to breathe again.

Reverse transcriptase: The enzyme that permits the human immunodeficiency virus (HIV) and other retroviruses to use their viral RNA as a template to make DNA.
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RNA: Short for ribonucleic acid, a nucleic acid molecule similar to DNA but containing ribose rather than deoxyribose. RNA is formed upon a DNA template. There are several classes of RNA molecules.
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Saliva: a watery secretion in the mouth produced by the salivary glands that aids in the digestion of food. Saliva also serves to moisten and cleanse the mouth, including the tongue and teeth, and contains substances that can play a role in the prevention of infection. Saliva aids digestion by moistening food and contains enzymes that begin the digestion process. Also known as spit.

Salmonella: A group of bacteria that cause typhoid fever and a number of other illnesses, including food poisoning, gastroenteritis and enteric fever from contaminated food products.
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Sarcoma: One of a group of tumors usually arising from connective tissue. Most sarcomas are malignant. Many types are named after the type of cell, tissue, or structure involved, as in angiosarcoma, chondrosarcoma, fibrosarcoma, liposarcoma,and osteosarcoma.

Sputum: The mucus and other matter brought up from the lungs, bronchi, and trachea that one may cough up and spit out or swallow. The word "sputum" is borrowed directly from the Latin "to spit." Called also expectoration.

Stage: As regards cancer, the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging.

Swallowing tube: Descriptive term for the esophagus. See: Esophagus.

Sweat: A colorless transparent acidic fluid with a distinctive odor secreted by the small tubular sudoriferous (sweat) glands situated within the skin and under it in the subcutaneous tissue. The sweat glands discharge their fluid through tiny openings in the surface of the skin.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Syphilis: A sexually transmitted disease caused by Treponema pallidum, a microscopic organism called a spirochete. This worm-like, spiral-shaped organism infects people by burrowing into the moist mucous membranes of the mouth or genitals. From there, the spirochete produces a non-painful ulcer known as a chancre. There are three stages of syphilis:
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Therapy: The treatment of disease.
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Transfusion: The transfer of blood or blood products from one person (the donor) into another person (the recipient's) bloodstream. In most situations, this is done as a lifesaving maneuver to replace blood cells or blood products lost through severe bleeding. Transfusion of your own blood (autologous) is the safest method but requires planning ahead and not all patients are eligible. Directed donor blood allows the patient to receive blood from known donors. Volunteer donor blood is usually most readily available and, when properly tested has a low incidence of adverse events.
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Tuberculosis: A highly contagious infection caused by the bacterium called Mycobacterium tuberculosis. Abbreviated TB. Tubercles (tiny lumps) are a characteristic finding in TB. Diagnosis may be made by skin test, which if positive should will be followed by a chest X-ray to determine the status (active or dormant) of the infection. Tuberculosis is more common in people with immune system problems, such as AIDS, than in the general population. Treatment of active tuberculosis is mandatory by law in the US, and should be available at no cost to the patient through the public health system. It involves a course of antibiotics and vitamins that lasts about six months. It is important to finish the entire treatment, both to prevent reoccurrence and to prevent the development of antibiotic-resistant tuberculosis. Most patients with tuberculosis do not need to be quarantined, but it is sometimes necessary.
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Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.

Vein: A blood vessel that carries blood low in oxygen content from the body back to the heart. The deoxygenated form of hemoglobin (deoxyhemoglobin) in venous blood makes it appear dark. Veins are part of the afferent wing of the circulatory system which returns blood to the heart.
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Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash."

Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
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Viruses: Small living particles that can infect cells and change how the cells function. Infection with a virus can cause a person to develop symptoms. The disease and symptoms that are caused depend on the type of virus and the type of cells that are infected.

Vomitus: Matter from the stomach that has come up into and may be ejected beyond the mouth, due to the act of vomiting.
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Wasting: 1. Gradual loss (for example, of weight), deterioration, emaciation. As in a wasting disease. 2. Excessive depletion. As in salt wasting, the excessive loss of salt.

Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).

Western blot: A technique in molecular biology, used to separate and identify proteins.
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Womb: The womb (uterus) is a hollow, pear-shaped organ located in a woman's lower abdomen between the bladder and the rectum. The narrow, lower portion of the uterus is the cervix; the broader, upper part is the corpus. The corpus is made up of two layers of tissue.

World Health Organization: An agency of the United Nations established in 1948 to further international cooperation in improving health conditions. Although the World Health Organization inherited specific tasks relating to epidemic control, quarantine measures, and drug standardization from the Health Organization of the League of Nations (that was set up in 1923) and from the International Office of Public Health at Paris (established in 1909), the World Health Organization was given a broad mandate under its constitution to promote the attainment of "the highest possible level of health" by all people. WHO defines health positively as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity."
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Yeast infection: Overgrowth of yeast can affect the skin (yeast rash), mouth (thrush), digestive tract, esophagus, vagina (vaginitis), and other parts of the body. Yeast infections occur most frequently in moist areas of the body. Although Candida albicans and other Candida yeasts are the most frequent offenders, other yeast groups are known to cause illness, primarily in immunocompromised patients. These include Torulopsis, Cryptococcus, Malassezia, and Trichosporon yeasts. Diagnosis is by observation, and can be confirmed by culturing a stool or mucosa sample, or a scraping from the affected area. Treatment is by topical or oral antifungal medications. Acidophilous, a helpful bacteria that normally helps to keep yeast in check, can also be tried in supplement form or in yogurt with live cultures.
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Zidovudine: See: AZT.