Mary D. Nettleman, MD, MS, MACP is the Chair of the Department of Medicine at Michigan State University. She is a graduate of Vanderbilt Medical School, and completed her residency in Internal Medicine and a fellowship in Infectious Diseases at Indiana University.
Dr. Daar received his undergraduate degree from UCLA and medical degree from Georgetown University School of Medicine. He completed an internship and residency in internal medicine at Cedars-Sinai Medical Center and his clinical and research fellowship in infectious diseases at Cedars-Sinai Medical Center and UCLA.
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
AIDS stands for "acquired immunodeficiency syndrome." AIDS is a disease
that weakens the immune system to the point where an affected person is
vulnerable to a wide range of infections and cancers that result in death if not
treated. AIDS is caused by the human immunodeficiency virus (HIV). The virus is
spread through contact with infected blood or secretions. At first (stage 1 HIV
infection), there is little evidence of harm. Over time, the virus attacks the
immune system, focusing on special cells called "CD4 cells" which are important
in protecting the body from infections and cancers, and the number of these
cells starts to fall (stage 2). Eventually, the CD4 cells fall to a critical
level and/or the immune system is weakened so much that it can no longer fight
off certain types of infections and cancers. This advanced stage of infection
(stage 3) with HIV is called AIDS.
HIV is a very small virus that contains ribonucleic acid (RNA) as its genetic
material. (Animal cells, plant cells, bacteria, parasites, and some viruses use
deoxyribonucleic acid [DNA] as their primary genetic material rather than RNA.)
When HIV infects animal cells, it uses a special enzyme, reverse transcriptase,
to turn (transcribe) its RNA into DNA which, in turn, directs the formation of
HIV RNA that can be used to form new HIV. This is different from the way human
cells reproduce (directly transcribing their DNA into RNA), so HIV is classified
as a "retrovirus." When HIV reproduces, it is prone to making small genetic
mistakes or mutations, resulting in viruses that vary slightly from each other.
This ability to create minor variations allows HIV to evade the body's
immunologic defenses, essentially leading to lifelong infection, and has made it
difficult to make an effective vaccine. The mutations also allow HIV to become
resistant to medications.
Pneumonia is inflammation of one or both lungs with consolidation. Pneumonia is frequently but not always due to infection. The infection may be bacterial, viral, fungal or parasitic. Symptoms may include fever, chills, cough with sputum production, chest pain, and shortness of breath.
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria. Symptoms include weakness, fever, weight loss, night sweats and in worse cases, chest pain, shortness of breath, and coughing up blood. A person with an active infection (a positive TB skin test, abnormal chest x-ray and TB bacteria in their sputum) requires treatment with izoniazid, rifampin, ethambutol and pyrazinaide.
HIV (human immunodeficiency virus) is the cause of AIDS (acquired immunodeficiency syndrome). HIV is a type of virus called a retrovirus, which infects humans when it comes in contact with a break in the skin or tissues such as those that line the vagina, anal area, mouth, or eyes.
Cellulitis is an acute spreading bacterial infection below the surface of the skin characterized by redness, warmth, inflammation, and pain. The most common cause of cellulitis is the bacteria Staph (Staphylococcus aureus).
Athlete's foot (tinea pedis) is a skin infection caused by the ringworm fungus. Symptoms include itching, burning, cracking, peeling, and bleeding feet. Treatment involves keeping the feet dry and clean, wearing shoes that can breathe, and using medicated powders to keep your feet dry.
Sexually transmitted diseases, or STDs,
are infections that are transmitted during any type of sexual exposure,
including intercourse (vaginal or anal), oral sex, and the sharing of sexual
devices, such as vibrators. Women can contract all of the STDs, but may have no symptoms, or have different symptoms than men do.
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Sexually transmitted diseases, or STDs, are infections that are transmitted during any
type of sexual exposure, including intercourse (vaginal or anal), oral sex, and
the sharing of sexual devices, such as vibrators. Although treatment exists for many STDs, others currently are
usually incurable, such as those caused by HIV, HPV, hepatitis B and C, and HHV-8.
Encephalopathy means brain disease, damage, or malfunction. Causes of encephalopathy are varied and numerous. The main symptom of encephalopathy is an altered mental state. Other symptoms include lethargy, dementia, seizures, tremors, and coma. Treatment of encephalopathy depends on the type of encephalopathy (anoxia, diabetic, Hashimoto's, hepatic, hyper - hypotensive, infectious, metabolic, infections, uremic, or Wernicke's) are examples of types of encephalopathy.
Toxoplasmosis (toxo) is a parasitic infection that causes flulike symptoms, swollen lymph nodes, and muscle aches and pains that may last from a few days to several weeks. Toxoplasmosis can be contracted by touching the hands to the mouth after gardening, cleaning a cat's litter box, or anything that came into contact with cat feces. Toxoplasmosis can also be contracted by eating raw or partly cooked meat, especially pork or lamb, or touching the hands to the mouth after contact with raw or undercooked meat.
Listeria is a type of bacteria that can cause food poisoning. Listeriosis symptoms include diarrhea, nausea and fever. Pregnant women are 20 times more likely than other healthy adults to get listeriosis. Listeria infection is treated with antibiotics.
It's important to know whether you will breastfeed or bottle-feed your baby prior to delivery, as the breasts' ability to produce milk diminishes soon after childbirth without the stimulation of breastfeeding. Breast milk is easily digested by babies and contains infection-fighting antibodies and cholesterol, which promotes brain growth. Formula-fed babies actually need to eat somewhat less often since formula is less readily digested by the baby than human milk. This article explores the advantages and disadvantages of both forms of feeding.
Histoplasmosis is a disease caused by the Histoplasma capsulatum fungus. Symptoms and signs of this infection are fever, dry cough, chills, malaise, sweats, and abdominal pain. Transmission of the infection occurs when people inhale the spores. Most infections resolve on their own, and resistant infections are treated with itraconazole, ketoconazole, or amphotericin B.
Keratitis is inflammation of the cornea. Symptoms and signs include pain, tearing, blurred vision, eye redness, watery eyes, or the cornea may appear gray or white. Treatment of keratitis depends upon the underlying cause of the inflammation.
Valley fever (coccidioidomycosis) is a disease caused by the inhalation of the Coccidioides immitis or C. posadasii fungus. Symptoms are flu-like and resolve over two to six weeks. Infection typically requires no treatment, though there are many antifungal drugs to treat valley fever.
Hemophilia is one of a group of inherited bleeding disorders. Hemophilia A and B are inherited in an X-linked recessive genetic pattern and is more common in males. Symptoms of hemophilia include bleeding into the joints, muscles, GI or urinary tract, or brain or skull. Treatments for hemophilia is generally replacement of blood clotting factors.
Cytomegalovirus (CMV) is a virus that is spread from person to person via spit, semen, vaginal secretions, urine, blood, sexual contact, breastfeeding, blood transfusions, organ transplants, and breast milk. Symptoms of CMV include fatigue, swollen glands, fever, and sore throat. You can take precautions to prevent CMV such as washing hands frequently and thoroughly, using condoms, if you work in day care centers wash hands thoroughly after contact with body secretions, and avoiding oral contact with objects covered in saliva. Individuals with HIV infection are at most risk of contracting CMV.
Cryptosporidiosis is an intestinal disease caused by the Cryptosporidium parasite. Symptoms include watery diarrhea, stomach cramps, nausea and vomiting, fever, weight loss, dehydration, and weight loss. Antibiotics are used in the treatment of cyptosporidiosis.
When you are pregnant, many sexually transmitted diseases (STDs) can be especially harmful to you and your baby. These STDs include herpes, HIV/AIDS, genital warts (HPV), hepatitis B, chlamydia, syphilis, gonorrhea, and trichomoniasis. Symptoms include bumps, sores, warts, swelling, itching, or redness in the genital region. Treatment of STDs while pregnant depends on how far along you are in the pregnancy and the progression of the infection.
Hospice is a service that offers support, resources, and assistance to terminally ill patients and their families. In such late stages of diseases, especially when there is "nothing left to do," hospice can offer help for patients and families. There are many aspects of a patient's well-being that can be addressed. Hospice can play a key role in managing physical symptoms of a disease (palliative care) and supporting patients and families emotionally and spiritually.
Histoplasmosis is a disease, usually affecting the lungs, caused by the
Histoplasma capsulatum fungus. Although many people that are or have been infected
with H. capsulatum do not appear ill, some people in the acute phase of the
disease have a dry cough, fever, and chest pains and do feel ill. There are
several types of histoplasmosis (acute, chronic, and disseminated, all with
subtypes).
H. capsulatum was first described by Samuel Darling in 1906 within human tissue cells
(histiocytes). In 1932, Katharine Dodd and Edna Tompkins made the first diagnosis of
histoplasmosis in an infant. Since the 1930s, H. capsulatum has been found
worldwide, but the majority of cases are found in river valleys in temperate
regions of the world and in equatorial Africa (in Africa, H. capsulatum has a
variant thick-walled yeast form termed H. duboisii). Often an outbreak occurs in
a group of ...
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