STORAGE: Acitretin should be stored between 15 C and 25 C (59 C and 77 F) and protected from light. Exposure to high temperatures and humidity should be avoided after the bottle is opened.
DOSING: The recommended dose is 25 to 50 mg daily given as a single dose with the main meal.
DRUG CLASS AND MECHANISM:
- Acitretin is an oral medication used to treat psoriasis. The mechanism of action of acitretin is unknown. It is chemically related to retinoic acid and retinol (vitamin A), and it reduces skin cell production and shedding. It takes several weeks to see its effects, up to 6 months to see a full response, and psoriasis may worsen before improvement is seen.
- The FDA approved acitretin in October 1996.
REFERENCE: FDA Prescribing Information
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