aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Other side effects include:

Aspirin should be avoided by patients with peptic ulcer disease or poor kidney function, since this medication can aggravate both conditions.

Aspirin may exacerbate asthma.

Aspirin can raise the blood uric acid level and is avoided in patients with hyperuricemia and gout.

Children and teenagers should avoid aspirin for symptoms of the flu or chickenpox because of the associated risk of Reye's Syndrome, a serious disease of the liver and nervous system that can lead to coma and death.

Aspirin can increase the effect of medicines used to treat diabetes mellitus, resulting in abnormally low blood sugars if blood sugar levels are not monitored.

NSAIDs should be discontinued prior to elective surgery because of a mild tendency to interfere with blood clotting. Aspirin, because of its prolonged effect on platelets, is best discontinued at least ten to fourteen days in advance of the procedure.

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS: Chewable tablets: 81mg; caplets and tablets: 325mg, 500mg; enteric coated (safety coated) caplets and tablets: 325mg, 500mg.

STORAGE: Aspirin should be stored at room temperature, 20 C to 25 C (68 F to 77 F), in a sealed container, avoiding moisture.

DOSING: Aspirin should be taken with food. Doses range from 50 mg to 6000 mg daily depending on the use.

  • Usual doses for mild to moderate pain are 350 or 650 mg every 4 hours or 500 mg every 6 hours.
  • Doses for rheumatoid arthritis include 500 mg every 4-6 hours; 650 mg every 4 hours; 1000 mg every 4-6 hours; 1950 mg twice daily.
  • Heart attacks are prevented with 81, 162 or 325 mg daily.

DRUG INTERACTIONS: Aspirin is associated with several suspected or probable interactions that affect the action of other drugs. The following examples are the most common of the suspected interactions.

Medically Reviewed by a Doctor on 1/26/2015


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