aspirin (acetylsalicylic acid, Ecotrin) (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
Aspirin should be avoided by patients with peptic ulcer disease or poor kidney function, since this medication can aggravate both conditions.
Children and teenagers should avoid aspirin for symptoms of the flu or chickenpox because of the associated risk of Reye's Syndrome, a serious disease of the liver and nervous system that can lead to coma and death.
Aspirin can increase the effect of medicines used to treat diabetes mellitus, resulting in abnormally low blood sugars if blood sugar levels are not monitored. NSAIDs should be discontinued prior to elective surgery because of a mild tendency to interfere with blood clotting. Aspirin, because of its prolonged effect on platelets, is best discontinued at least ten to fourteen days in advance of the procedure.
GENERIC AVAILABLE: Yes
PREPARATIONS: Chewable tablets: 81mg; caplets and tablets: 325mg, 500mg; enteric coated (safety coated) caplets and tablets: 325mg, 500mg.
STORAGE: Aspirin should be stored at room temperature, 20-25 C (68-77 F), in a sealed container, avoiding moisture.
DOSING: Aspirin should be taken with food. Doses range from 50 mg to 6000 mg daily depending on the use.
DRUG INTERACTIONS: Aspirin is associated with several suspected or probable interactions that affect the action of other drugs. The following examples are the most common of the suspected interactions.
NSAIDs may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.
Medically Reviewed by a Doctor on 12/29/2014
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