aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

A Guide to Migraine Headaches

SIDE EFFECTS: Most patients benefit from aspirin and other NSAIDs with few side effects. However, serious side effects can occur and generally tend to be dose-related. Therefore, it is advisable to use the lowest effective dose to minimize side effects.

The most common side effects of aspirin involve the gastrointestinal system and ringing in the ears.

Gastrointestinal side effects are

  • ulcerations,
  • abdominal burning,
  • pain,
  • cramping,
  • nausea,
  • gastritis, and
  • even serious gastrointestinal bleeding and
  • liver toxicity.

Sometimes, ulceration and bleeding can occur without any abdominal pain. Black tarry stools, weakness, and dizziness upon standing may be the only signs of internal bleeding.

Ringing in the ears

Other side effects include:

Other side effects and adverse reactions

  • Aspirin should be avoided by patients with peptic ulcer disease or poor kidney function, since this medication can aggravate both conditions.
  • Aspirin may exacerbate asthma.
  • Aspirin can raise the blood uric acid level and is avoided in patients with hyperuricemia and gout.
  • Children and teenagers should avoid aspirin for symptoms of the flu or chickenpox because of the associated risk of Reye's Syndrome, a serious disease of the liver and nervous system that can lead to coma and death.
  • Aspirin can increase the effect of medicines used to treat diabetes mellitus, resulting in abnormally low blood sugars if blood sugar levels are not monitored.
  • NSAIDs should be discontinued prior to elective surgery because of a mild tendency to interfere with blood clotting. Aspirin, because of its prolonged effect on platelets, is best discontinued at least ten to fourteen days in advance of the procedure.

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS: Chewable tablets: 81mg; caplets and tablets: 325mg, 500mg; enteric coated (safety coated) caplets and tablets: 325mg, 500mg.

STORAGE: Aspirin should be stored at room temperature, 20 C to 25 C (68 F to 77 F), in a sealed container, avoiding moisture.

Medically Reviewed by a Doctor on 7/30/2015

Quick GuideMigraine or Headache? Migraine Symptoms, Triggers, Treatment

Migraine or Headache? Migraine Symptoms, Triggers, Treatment
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