aspirin (acetylsalicylic acid, Ecotrin) (cont.)

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PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS: Chewable tablets: 81mg; caplets and tablets: 325mg, 500mg; enteric coated (safety coated) caplets and tablets: 325mg, 500mg.

STORAGE: Aspirin should be stored at room temperature, 20-25 C (68-77 F), in a sealed container, avoiding moisture.

PRESCRIBED FOR: Aspirin is used for the treatment of inflammation, fever, and pain that results from many forms of arthritis, including rheumatoid arthritis, juvenile arthritis, systemic lupus erythematosus, ankylosing spondylitis, Reiter's syndrome, and osteoarthritis, as well as for soft tissue injuries, such as tendinitis and bursitis. Aspirin also is used for rapid relief of mild to moderate pain and fever in other inflammatory conditions. Because aspirin inhibits the function of platelets for prolonged periods of time, it is used for reducing the risk of strokes and heart attacks.

DOSING: Aspirin should be taken with food. Doses range from 50 mg to 6000 mg daily depending on the use.

  • Usual doses for mild to moderate pain are 350 or 650 mg every 4 hours or 500 mg every 6 hours.
  • Doses for rheumatoid arthritis include 500 mg every 4-6 hours; 650 mg every 4 hours; 1000 mg every 4-6 hours; 1950 mg twice daily.
  • Heart attacks are prevented with 81, 162 or 325 mg daily.

DRUG INTERACTIONS: Aspirin is associated with several suspected or probable interactions that affect the action of other drugs. The following examples are the most common of the suspected interactions.

NSAIDs may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.

Aspirin may reduce the blood pressure lowering effects of blood pressure medications. This may occur because prostaglandins have a role in the regulation of blood pressure.



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