GENERIC NAME: ACETYLCYSTEINE - INJECTION (a-set-ill-SIST-een)
BRAND NAME(S): Acetadote
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is used as an antidote for acetaminophen overdose to prevent life-threatening liver damage. It is most effective if given within 8 to 10 hours after ingestion, but it can be used anytime up to 24 hours after an overdose. If acetaminophen overdose is suspected, but the exact time of ingestion is unknown, acetylcysteine may still be given.
HOW TO USE: Before and during use of this medication, acetaminophen blood levels will be taken. The first blood test should be done no later than 4 hours after the suspected ingestion. A repeat blood test may be necessary (e.g., in case of extended-release acetaminophen overdose). Additional blood tests will determine if treatment should be continued. This medication is injected into a vein (intravenously-IV) by a healthcare professional, or as directed by your doctor. The dosage is based on your weight. This drug should be continued until your acetaminophen blood levels are below toxic levels. Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have any questions regarding the use of this medication, consult your pharmacist. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Discard the remaining content of any open vials immediately after use.
SIDE EFFECTS: Nausea, vomiting, dizziness, flushing, stomach upset, cough, or increased sweating may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: eye pain, fainting, trouble walking. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling (especially of the face, lips, tongue, or throat), severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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