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February 10, 2012
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abciximab - injection, Reopro (cont.)

PRECAUTIONS: Before using abciximab, tell your doctor or pharmacist if you are allergic to it; or to mouse proteins; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: current bleeding, bleeding from the gut or bladder in the last 6 weeks (e.g., bleeding peptic ulcer), stroke in the last 2 years, history of stroke with continuing problems (e.g., slurred speech, weak muscles, vision problems), major surgery/injury/other bleeding in the last 6 weeks, brain tumor, blood vessel problem in the brain (e.g., aneurysm, AV malformation), very high uncontrolled blood pressure, inflammation of the blood vessels (vasculitis).Before using this medication, tell your doctor or pharmacist your medical history, especially of: use of this drug in the last 30 days, stomach/intestinal problems (e.g., peptic ulcer, inflammatory bowel disease), low blood platelets (thrombocytopenia), liver disease.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medication because a very serious interaction may occur: dextran.If you are currently using the medication listed above, tell your doctor or pharmacist before starting abciximab.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other "blood thinners" (e.g., warfarin) used in the last 7 days, NSAIDs (e.g., ibuprofen, naproxen), anti-platelet drugs (e.g., dipyridamole, ticlopidine), tipranavir.Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, or aspirin) that are similar to this drug.Abciximab is often used with other "blood thinners" such as aspirin, clopidogrel, and heparin. Be sure to check with your doctor or pharmacist regarding which medicines you need to take after leaving the hospital. Low-dose aspirin should be continued if prescribed by your doctor for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day). Consult your doctor or pharmacist for more details.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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