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GENERIC NAME: ABCIXIMAB - INJECTION (ab-SIX-eh-mab)

BRAND NAME(S): Reopro

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication keeps blood cells (platelets) from sticking together. It is used during certain heart artery procedures (e.g., angioplasty).

HOW TO USE: This medication is given by injection usually 10 to 60 minutes prior to the procedure followed by a continuous infusion into a vein for up to 12 hours. Your dose will be determined by your condition and response. Do not increase the dose, use it more often or continue using this drug longer than prescribed. Do not shake container.

SIDE EFFECTS: Nausea, vomiting, dizziness or irritation at the injection site may occur. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you experience: bruising or bleeding, skin rash, breathing trouble, rapid or abnormal heartbeat, chest pain, swelling of the feet or ankles. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Should not be used if there is any bleeding (e.g., gastrointestinal bleeding) or history of stroke. Should be used carefully if at all in patients weighing less than 75 Kg or older than 65 years or have a history of gastrointestinal disease. Tell your doctor if you have: other illnesses, recent surgeries or trauma, any allergies. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Should not be used with dextran or thrombolytics. Tell your doctor of any over-the-counter or prescription medication you use, including: blood thinners taken within 7 days, aspirin, NSAIDs (e.g., ibuprofen), ticlopidine. Do not start or stop any medicine without doctor or pharmacist approval.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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  • Peripheral Vascular Disease - Peripheral vascular disease (PVD) refers to diseases of the blood vessels (arteries and veins) located outside the heart and brain. PVD is sometimes referred to as peripheral artery disease. Symptoms include intermittent claudication, rest pain, numbness in the extremities and more.
  • Aspirin and Antiplatelet Medications - Read about aspirin therapy to prevent heart attack and stroke. Also learn about other anti-platelet medications such as, thienopyridines, and glycoprotein IIB/IIa inhibitors.

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abciximab-injection, Reopro

What is aspirin?

Aspirin belongs to a class of medications called nonsteroidal antiinflammatory drugs (NSAIDs). Aspirin and other NSAIDs, for example, ibuprofen (for example, Motrin, Advil) and naproxen (for example, Aleve), are widely used to treat fever, pain, and inflammatory conditions such as arthritis, tendonitis, and bursitis. Aspirin is known chemically as acetyl salicylic acid and often abbreviated as ASA.

In addition to its effects on pain, fever, and inflammation, aspirin also has an important inhibitory effect on platelets in the blood. This antiplatelet effect is used to prevent blood clot formation inside arteries, particularly in individuals who have atherosclerosis (narrowing of the blood vessels) of their arteries, or are otherwise prone to develop blood clots in their arteries.

What are antiplatelet agents?

Antiplatelet agents are medications that block the formation of blood clots by pre...

Read the Aspirin and Antiplatelet Medications article »



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