abacavir, lamivudine, zidovudine, Trizivir (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: Trizivir causes the same side effect as its component drugs, abacavir, lamivudine and zidovudine. The most common side effects are:

Serious and sometimes fatal hypersensitivity reactions involving several organs have been associated with abacavir, a component of Trizivir. Symptoms include fever, rash, nausea, vomiting, diarrhea, abdominal pain, fatigue, aches, shortness of breath, cough, and sore throat. Patients should discontinue Trizivir if a hypersensitivity reaction is suspected. Patients who carry a certain genetic marker called HLA-B 5701 are at high risk for experiencing a hypersensitivity reaction to abacavir. Screening for the HLA-B 5701 allele is recommended prior to initiating therapy with abacavir.

Other important side effects of the abacavir component include:

GENERIC AVAILABLE: No.

PRESCRIPTION: Yes.

PREPARATIONS: Tablets: 300 mg abacavir/150 mg lamivudine/300 mg zidovudine.

Medically Reviewed by a Doctor on 6/10/2015


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