abacavir, lamivudine, zidovudine, Trizivir

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

HIV/AIDS Myths and Facts

GENERIC NAME: abacavir, lamivudine, zidovudine

BRAND NAME: Trizivir

DRUG CLASS AND MECHANISM: Trizivir is a combination oral medication that is used for treating infections with the human immunodeficiency virus (HIV). Trizivir contains abacavir (Ziagen), lamivudine (Epivir) and zidovudine (Retrovir), which are three different anti-HIV drugs with different mechanisms of action. Anti-HIV drugs are often used in combination to increase HIV suppression and to reduce the chance of the HIV developing resistance to any single drug. Combining these three drugs into one pill reduces the number of individual medications that a patient has to take, which makes it easier for patients to comply with therapy. Administration of one tablet of Trizivir is equal to giving 300 mg of abacavir, 150 mg of lamivudine and 300 mg of zidovudine together. Trizivir does not reduce the transmission of HIV among individuals, and it does not cure HIV or AIDS. Trizivir was approved by the FDA in November 2000.

PRESCRIBED FOR: Trizivir is used alone or in combination with other anti-HIV drugs for the treatment of HIV infection.

SIDE EFFECTS: Trizivir causes the same side effect as its component drugs, abacavir, lamivudine and zidovudine. The most common side effects are:

Medically Reviewed by a Doctor on 6/10/2015

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