abacavir, Ziagen (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
PRESCRIBED FOR: Abacavir is used in combination with other anti-HIV drugs for the treatment of HIV infection.
SIDE EFFECTS: The most common side effects are:
The most serious side effects are severe allergic reactions, pancreatitis, liver failure, and metabolic disturbance (lactic acidosis). Symptoms of an allergic reaction include skin rash, fever, weakness, swelling and difficulty breathing. Abacavir must be stopped as soon an allergic reaction is suspected, and it should not be restarted after an allergic reaction.
GENERIC AVAILABLE: No
PREPARATIONS: Tablets: 300 mg; oral solution: 20 mg/ml
STORAGE: Capsules and solution should be stored at room temperature, 15C to 30 C (59 F to 86F). The oral solution may be refrigerated but should not be frozen.
DOSING: The recommended dose for adults is 300 mg twice daily or 600 mg once daily. Children (3 months and older) should receive 8 mg/kg twice daily of the solution, and the maximum recommended dose is 300 mg twice daily. Pediatric patients weighing 14 kg or more may also be treated with abacavir tablets at doses of 300, 450, or 600 mg daily based on weight. Abacavir may be administered with or without food since food does not affect its absorption.
Medically Reviewed by a Doctor on 6/10/2015
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